Evidence map›Paper›PMID 41271198›Full record

ArticleJournal of the American Chemical Society2025

Short, Enantioselective Total Synthesis of (+)-Ineleganolide.

Kuan Yu, Aikaterini Gorou, Danny Huang, Thomas J Maimone

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Asymmetric Total Synthesis of (+)-Ineleganolide.Angewandte Chemie (International ed. in English) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kuan YuDepartment of Chemistry, University of California─Berkeley, 826 Latimer Hall, Berkeley, California 94720, United States.ORCID 0009-0001-7605-7033
Aikaterini GorouDepartment of Chemistry, University of California─Berkeley, 826 Latimer Hall, Berkeley, California 94720, United States.
Danny HuangDepartment of Chemistry, University of California─Berkeley, 826 Latimer Hall, Berkeley, California 94720, United States.
Thomas J MaimoneDepartment of Chemistry, University of California─Berkeley, 826 Latimer Hall, Berkeley, California 94720, United States.ORCID 0000-0001-5823-692X

Funding

Synthesis of Complex Terpenes From Simple Precursors: RenewalR01GM116952 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MAIMONE, THOMAS JOHN · 2016 to 2024
$2.7M
New Bond Disconnections in the Streamlined Synthesis of Complex Bioactive MoleculesR35GM156482 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Thomas John Maimone · 2025 to 2026
$986k
GPU Computing Cluster for Transformative Public Health driven Molecular ScienceS10OD034382 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI DURKIN, KATHLEEN A · 2023 to 2023
$491k
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NIGMS NIH HHS R01 GM116952NIGMS NIH HHS R35 GM156482NIH HHS S10 OD024998NIH HHS S10 OD034382
6 · The paper itself

Abstract

Owing to their distinctive polycyclic architectures and promising bioactivities, the large family of furanocembranoid natural products continues to attract significant attention from the synthetic community. Herein, we present a 10-step total synthesis of (+)-ineleganolide, a highly oxidized norcembranoid natural product featuring a synthetically challenging caged pentacyclic framework. An interesting

Identifiers

PMID41271198
PMCPMC12703658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.