Evidence map›Paper›PMID 41270747›Full record

ReviewStem cell reports2025

Community and bioethicists' perspectives on iPSC research with biobanked samples collected using broad consent.

P A Ikhane, T Yusuf, O Adeyemo, T O Ogundiran, S N Adebamowo, C A Adebamowo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The Continuity Trap in Data Science Health Research.Journal of medical Internet research · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

P A IkhaneDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Research, Center for Bioethics and Research, Ibadan, Nigeria; Department of Bioethics and Medical Humanities, University of Ibadan, Ibadan, Nigeria.
T YusufDepartment of Research, Center for Bioethics and Research, Ibadan, Nigeria.
O AdeyemoDepartment of Research, Center for Bioethics and Research, Ibadan, Nigeria.
T O OgundiranDepartment of Research, Center for Bioethics and Research, Ibadan, Nigeria; Department of Bioethics and Medical Humanities, University of Ibadan, Ibadan, Nigeria; Department of Surgery, University of Ibadan, Ibadan, Nigeria.
S N AdebamowoDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Greenebaum Comprehensive Cancer, University of Maryland School of Medicine, Baltimore, MD, USA.
C A AdebamowoDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Research, Center for Bioethics and Research, Ibadan, Nigeria; Department of Bioethics and Medical Humanities, University of Ibadan, Ibadan, Nigeria; Greenebaum Comprehensive Cancer, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: cadebamowo@som.umaryland.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using anonymized, biobanked samples for induced pluripotent stem cells (iPSCs) creates new and unresolved ethical dilemmas. To elucidate the issues, we studied the perspectives of community members and bioethicists involved in the collection of the Yoruba Resident in Ibadan, Nigeria (YRI) HapMap samples. We found support for broad consent, commercial use of samples, more benefit sharing, sustained engagement of the community and local researchers, particularly for novel research, where a long time has elapsed between samples' collection and new research projects, and in the oversight of biobanked samples. Broad consent was durable when coupled with sustained community engagement, transparent governance, and practical mechanisms for reciprocal benefit.

Indexed as

Biological Specimen BanksEthicistsInduced Pluripotent Stem CellsInformed ConsentStem Cell ResearchHumansNigeria

Identifiers

PMID41270747
PMCPMC12744847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.