Evidence map›Paper›PMID 41270399›Full record

ArticleSchizophrenia research2026

Epidemiological analysis of schizophrenia and incarceration: A multi-center exploration of the criminalization of mental illness in the United States.

Nikita Das, Ravi Dhamija, Dan Mistak, Laurel D Diaz, David C Kaelber, Karen Mulloy, Tani Malhotra, Vanessa Maier

Abstract readMulticenter Study
In one paragraph

Article in Schizophrenia research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nikita DasCase Western Reserve University School of Medicine, Cleveland, OH, United States of America. Electronic address: nxd277@case.edu.
Ravi DhamijaCase Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Dan MistakHealth Care Initiative for Justice-Involved Populations at Community Oriented Correctional Health Services, Oakland, CA, United States of America.
Laurel D DiazCuyahoga County Justice and Health Equity Office, Cleveland, OH, United States of America.
David C KaelberCenter for Clinical Informatics Research & Education, The MetroHealth System, Case Western Reserve University, Cleveland, OH, United States of America; Department of Internal Medicine, Case Western Reserve University, Cleveland, OH, United States of America; Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States of America; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States of America.
Karen MulloyCase Western Reserve University School of Medicine, Cleveland, OH, United States of America; Swetland Center for Environmental Health, Case Western Reserve University, Cleveland, OH, United States of America.
Tani MalhotraCase Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Vanessa MaierCase Western Reserve University School of Medicine, Cleveland, OH, United States of America.

Funding

Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
NCATS NIH HHS UM1 TR004528
6 · The paper itself

Abstract

objectiveThis study investigates the diagnostic relationship between schizophrenia and incarceration and elucidates a temporal relationship between these conditions.

methodsThis analysis utilized TriNetX (December 2024), querying 60+ U.S. Healthcare Organizations using ICD-10-CM codes to compare the prevalence ratio (PR) of schizophrenia in patients with and without electronic health record (EHR) documented incarceration, and conversely, to compare the PR of incarceration in patients with and without schizophrenia. An additional cumulative incidence ratio (CIR) analysis was performed to compare cumulative incidence of incarceration after schizophrenia diagnosis to that of incarceration before diagnosis.

resultsOf 80,224 patients with incarceration history, 7.35 % had schizophrenia, compared to 0.36 % among those without incarceration (PR: 20.3, 95 % C.I. 19.8-20.8). Of 423,270 people with schizophrenia, 1.4 % had incarceration history compared to 0.06 % among people without schizophrenia (PR: 21.6, 95 % C.I. 21.0-22.1). Schizophrenia followed incarceration in 1.5 % of cases, while incarceration followed schizophrenia in 0.93 % (CIR: 0.62 %, 95 % C.I. 0.53-0.71 %).

conclusionsSchizophrenia is overrepresented in incarcerated populations, and incarceration may be a risk factor for schizophrenia presentation. Adopting a medicalized approach to criminal justice may help alleviate the U.S.'s mass incarceration crisis.

Indexed as

CriminalsPrisonersSchizophreniaAdultFemaleHumansIncarcerationIncidenceMaleMiddle AgedPrevalenceUnited StatesCriminal justiceIncarcerationMental illnessSchizophrenia

Identifiers

PMID41270399
PMCPMC12752710

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.