Evidence map›Paper›PMID 41270220›Full record

ArticleEuropean journal of neurology2025

Impact of Collateral Circulation on Poststroke Epilepsy After Mechanical Thrombectomy for Large Vessel Occlusive Stroke: A Multicenter Cohort Study.

Peng Jiang, Zongzhi Jiang, He Sui, Mingyang Du, Qi Guo, Zhaoshi Zheng, Fuli Wang, Zhanhao Mo, Songyan Liu

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng JiangDepartment of Neurology, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, China.ORCID 0009-0007-8219-2665
Zongzhi JiangDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
He SuiDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
Mingyang DuDepartment of Intervention, Shengjing Hospital of China Medical University, Shenyang, China.
Qi GuoDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
Zhaoshi ZhengDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
Fuli WangDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
Zhanhao MoDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.
Songyan LiuDepartment of Neurology, China-Japan Union Hospital, Jilin University, Changchun, China.ORCID 0000-0003-0619-2755

Funding

China-Japan Union Hospital of Jilin University, "Study on the construction and clinical application of a risk warning model for epilepsy after ischemic stroke based on multimodal radiomics and clinical features" YJZ2024001
6 · The paper itself

Abstract

backgroundAcute ischemic stroke (AIS) represents a significant etiology of acquired epilepsy in adults. However, there remains a paucity of evidence concerning predictive factors for poststroke epilepsy (PSE) among patients undergoing mechanical thrombectomy (MT). We aimed to evaluate the association between poor collateral circulation and the risk of PSE.

methodsThis multicenter cohort study included AIS patients who underwent MT (2017-2022) at three tertiary centers. Adjusted Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for PSE risk. Subgroup analyses, sensitivity analyses, and competing risk analyses were also performed.

resultsWe included 1167 patients (mean age: 62 years; 46.5% female). PSE frequency was higher in the poor collateral circulation group compared to the control group (13.0% vs. 4.2%, p < 0.001). Patients with inadequate collateral circulation (ASITN/SIR < 2) showed significantly increased risks of both 12-month PSE and 60-month PSE development (HR > 1, p < 0.05) compared to those with adequate collateral status (ASITN/SIR ≥ 2) following MT for AIS.

conclusionsPoor collateral circulation is associated with PSE and may help identify individuals at high risk for PSE.

Indexed as

Collateral CirculationEpilepsyIschemic StrokePostoperative ComplicationsThrombectomyAgedCohort StudiesFemaleHumansMaleMiddle Agedcollateral circulationepilepsyrisk assessmentstrokethrombectomy

Identifiers

PMID41270220
PMCPMC12637856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.