Evidence map›Paper›PMID 41270094›Full record

ArticlePLOS global public health2025

Barriers and facilitators to integrating tuberculosis treatment into community pharmacies for people with TB/HIV in Kampala, Uganda: A qualitative study.

Jonathan Izudi, Adithya Cattamanchi, Christine Sekaggya-Wiltshire, Noah Kiwanuka, Amanda Sammann, Rachel King

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan IzudiDirectorate of Graduate Training, Research and Innovation, Muni University, Arua, Uganda.ORCID https://orcid.org/0000-0001-9065-0389
Adithya CattamanchiDivision of Pulmonary Diseases and Critical Care Medicine, University of California Irvine, Irvine, California, United States of America.
Christine Sekaggya-WiltshireResearch Department, Makerere University Infectious Diseases Institute, Kampala, Uganda.
Noah KiwanukaDepartment of Epidemiology and Biostatistics, School of Public Health, Makerere University, Kampala, Uganda.
Amanda SammannDepartment of Surgery, University of California San Francisco (UCSF), California, United States of America.ORCID https://orcid.org/0000-0002-8044-7165
Rachel KingInstitute for Global Health Sciences, University of California San Francisco (UCSF), California, United States of America.ORCID https://orcid.org/0000-0002-0085-3498

Funding

Integrating tuberculosis treatment into community pharmacies to improve TB/HIV outcomes in Uganda.K43TW012839 · FIC · INFECTIOUS DISEASES INSTITUTE · PI Jonathan Izudi · 2024 to 2026
$329k
FIC NIH HHS K43 TW012839
6 · The paper itself

Abstract

Community pharmacies (private retail drug shops or pharmacies) have proven successful for delivering anti-retroviral therapy to people living with human immunodeficiency virus (HIV). Leveraging this model for tuberculosis (TB) treatment integration could improve access to both TB and HIV treatment among people with TB/HIV. We identified the barriers and facilitators to integrating TB treatment into community pharmacies for people with TB/HIV in Kampala, Uganda, using a qualitative study across six public health facilities. Participants included people with TB/HIV; healthcare providers (HCPs) from the six facilities and their affiliated community pharmacies; and experts from the Ministry of Health. Data were collected through interviews guided by the Consolidated Framework for Implementation Research (CFIR). We performed framework analysis and mapped the emergent sub-themes to the relevant CFIR domains. We enrolled 47 participants: six TB focal persons, six HIV focal persons, nine pharmacy HCPs, three Ministry of Health staff, and 23 people with TB/HIV. Major facilitators included the convenience of accessing both TB and HIV treatment at a single location; enhanced privacy and reduced stigma; improved accessibility through extended hours, shorter wait times, and proximity; readiness of community pharmacy HCPs to deliver TB treatment; willingness of people with TB/HIV to engage in self-managed care; and training of pharmacy HCPs in TB care. Key barriers included unclear eligibility criteria for enrolling people with TB/HIV, absence of TB counseling services at pharmacies, inadequate infrastructure for TB drug storage, limited confidence among pharmacy HCPs in delivering TB care, and unclear logistics and operational procedures for implementation. Therefore, context-specific interventions that are developed in collaboration with key stakeholders, address barriers like eligibility criteria refinement, enhanced pharmacy HCP training, and financial incentives, and leverage facilitators like policy support and stakeholder readiness, are needed for the successful integration of TB treatment into community pharmacies for people with TB/HIV in Uganda.

Identifiers

PMID41270094
PMCPMC12637944

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.