Evidence map›Paper›PMID 41270056›Full record

ArticlePloS one2025

Evaluation of a "one-stop shop" for integrated harm reduction and primary care for people who inject drugs.

Nadeen Ibrahim, Shaifer Jones, Katherine Rich, Lisandra Alvarez, Carolina Price, Natalie Kil, Frederick L Altice, Jaimie P Meyer

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadeen IbrahimNIDA Summer Internship Program, Bethesda, Maryland, United States of America.ORCID https://orcid.org/0009-0009-4409-767X
Shaifer JonesYale School of Medicine, New Haven, Connecticut, United States of America.ORCID https://orcid.org/0009-0007-8442-2233
Katherine RichHarvard Medical School, Boston, Massachusetts, United States of America.
Lisandra AlvarezDepartment of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America.
Carolina PriceDepartment of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America.
Natalie KilDepartment of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America.
Frederick L AlticeDepartment of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America.
Jaimie P MeyerDepartment of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America.ORCID https://orcid.org/0000-0001-5735-385X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople who inject drugs (PWID) experience high risk for HIV and HCV infection, which can be mitigated by harm reduction strategies, including syringe service programs (SSP). Understanding individuals' patterns of substance use and SSP utilization is important for optimizing harm reduction strategies and disease prevention for PWID.

methodsWe evaluated demographic characteristics and service utilization from the New Haven Syringe Services Program (NHSSP), a low-threshold service delivery site in New Haven, Connecticut that provides fully integrated harm reduction and primary healthcare services to PWID. Site-specific data were extracted from the e2ctprevention database, managed by the Connecticut Department of Public Health, and EvaluationWeb from January 2017 to October 2023. We conducted a descriptive analysis of basic demographic and social characteristics of SSP clients, transaction characteristics, and service utilization. Statistical analyses were conducted using STATA v 16.1 and IBM SPSS Statistics (v 29.0.2.0).

resultsAmong 1,189 unique individuals utilizing SSP during the observation period, most (65.2%) identified as men and white (73.3%), consistent with SSP clients regionally and nationally. The mean age of clients was 41 years (SD = 9.8); approximately half of participants were unstably housed and 80% were unemployed at intake. From June 2020 to October 2023, there were 7,238 transactions, which increased throughout the COVID-19 pandemic period. During this period, the program dispensed 1,860,621 syringes, in addition to other materials, including overdose education and naloxone distribution (OEND), and provided patient education on safer injecting techniques and wound care.

conclusionIn this first comprehensive analysis of a large SSP since its inception and through the COVID-19 pandemic, we described important client characteristics and utilization of an array of syringe services from an integrated SSP. Findings suggest the SSP attracts a high volume of clients, provides on-demand services, and reaches a wide range of clients. Future research is needed to evaluate the impact of the program's home-delivery service and increased outreach efforts. Despite limitations, the program's success demonstrates the SSP can serve as a model for other harm reduction programs nationally.

Indexed as

Harm ReductionNeedle-Exchange ProgramsPrimary Health CareSubstance Abuse, IntravenousAdultConnecticutCOVID-19FemaleHepatitis CHIV InfectionsHumansMaleMiddle AgedYoung Adult

Identifiers

PMID41270056
PMCPMC12637901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.