ArticlePloS one2025
Longitudinal modeling of health-related quality of life trajectories over 12 months following road trauma.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From Injury to Recovery: A Six-Month Longitudinal Analysis of Quality of Life After Adult Trauma.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study identified the potential phases of health-related quality of life (HRQoL) change over a year following road trauma (RT) injury, as well as its predictors.
methodsThis inception cohort study recruited 1480 Canadian RT survivors from July 2018 to March 2020. HRQoL outcome was assessed with the 5-level version of the EuroQol (EQ-5D-5L) instrument at baseline (pre-injury) and at 2, 4, 6, and 12 months post-injury. Predictors of HRQoL included sociodemographic, psychological, medical, and trauma-related factors collected at baseline. We applied generalized additive mixed models to flexibly capture nonlinear changes in HRQoL over time, and piecewise latent growth curve model to analyze distinct linear phases of recovery across defined time intervals.
resultsThe estimated trajectory of EQ-5D-5L summary and EQ-VAS scores were lower than baseline at 2-months (phase 1), and then increased (phase 2), but did not return to baseline values at 12-months. White ethnicity, higher somatic symptom, pain catastrophizing, and use of medication pre-injury were associated with lower pre-injury EQ-5D-5L summary and EQ-VAS scores. Phase 1 EQ-5D-5L decreases were associated with female sex, no pre-existing body complaints, lack of expectation for a fast recovery, higher ISS, higher injury pain, and neck, spine/back, upper extremity, or lower extremity injuries. Phase 1 EQ-VAS decreases were associated with female sex, lower somatic symptom, fewer comorbidities, lack of expectation for a fast recovery, higher ISS, higher injury pain, neck, spine/back or lower extremity injuries. In phase 2, EQ-5D-5L summary improved most in participants with higher education levels and longer recovery expectations; EQ-VAS improved most in cyclists and patients with longer recovery expectations.
conclusionsClinicians should assess and address patients' recovery expectations early in the care process, as these may significantly influence long-term HRQoL outcomes. Incorporating strategies to support realistic yet positive expectations, such as cognitive-behavioral therapy, structured patient education, and goal-setting programs, may improve recovery experiences. In addition, identifying patients with high pain, or specific injury types may help target early interventions to those at risk of poor HRQoL trajectories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.