ArticleMethods in molecular biology (Clifton, N.J.)2026
Establishment of Adult Stem Cell-Derived Organoid Cultures: General Principles from the Mouse Gut.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Organoid models: applications and research advances in gastric cancer.Frontiers in oncology · 2026Review
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult stem cell (ASC)-derived organoid cultures have become an important model system for studying mammalian epithelial tissues in health and disease, including autoimmune conditions. Somatic stem cells are isolated and embedded into basement membrane-like matrix to allow for the in vitro outgrowth of miniature versions of functional epithelium in the presence of supportive growth factor niche. Organoids derived from tissues affected by autoimmune diseases, such as the intestine in inflammatory bowel disease or salivary glands in Sjögren's disease, may provide an invaluable platform for exploring disease mechanisms, immune-epithelial interactions, and therapeutic interventions. Here, we describe the basic establishment and maintenance principles of mouse intestinal organoid cultures, suitable for many downstream applications, including for disease modeling, drug discovery, and regenerative medicine.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.