Evidence map›Paper›PMID 41269490›Full record

ReviewPharmacoEconomics2026

The 'Values in Modelling' Framework for Patient and Public Involvement in Health Economics Modelling: Development and Application in the LEAP Model Project.

Stephanie Harvard, Rachel Carter, Sian Hoe Cheong, Tony Lanier, Zainab Zeyan, Amin Adibi, Spencer Lee, Cristina Novacovik, Mark Ewert, Eric B Winsberg and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in PharmacoEconomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie HarvardDivision of Respiratory Medicine, University of British Columbia (UBC), Gordon and Leslie Diamond Health Care Centre, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada. stephanie.harvard@ubc.ca.ORCID http://orcid.org/0000-0002-9008-2163
Rachel CarterLegacy for Airway Health Community Partner Committee, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0001-8609-798X
Sian Hoe CheongLegacy for Airway Health Community Partner Committee, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Tony LanierLegacy for Airway Health Community Partner Committee, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Zainab ZeyanLegacy for Airway Health Community Partner Committee, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Amin AdibiLegacy for Airway Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Spencer LeeFaculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Cristina NovacovikFaculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Mark EwertFaculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Eric B WinsbergDepartment of History and Philosophy of Science, University of Cambridge, Free School Lane, Cambridge, CB2 3RH, UK.ORCID http://orcid.org/0000-0002-8764-0072
Kate M JohnsonDivision of Respiratory Medicine, University of British Columbia (UBC), Gordon and Leslie Diamond Health Care Centre, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada.ORCID http://orcid.org/0000-0001-7406-2448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient and public involvement (PPI) in health economics modelling is increasingly recommended, yet formal guidance for how to structure or evaluate it remains limited. The Values in Modelling (VIM) framework was developed to address this gap by helping teams identify and deliberate on value-laden decisions in modelling. Drawing on philosophical theory, the framework defines five steps to guide collaboration between modellers and transdisciplinary participators and to document their influence on decision making: (1) identify ethical issues and perspectives; (2) characterize modelling decisions; (3) select decision-making strategies; (4) deliberate 'open' decisions; and (5) report and evaluate. We applied the VIM framework in the Lifetime Exposures and Asthma Outcomes Projection (LEAP) model project, which models the cost effectiveness of high-efficiency particulate air (HEPA) filters for asthma prevention and management. In this application, the framework helped prioritize modelling decisions for PPI, supported transparent deliberation about uncertainty, and led to concrete methodological changes-including new sensitivity analyses and revised outcome measures. These results demonstrate how a theory-informed process can enhance PPI in modelling, improving transparency, justification, and adequacy-for-purpose in health economics research.

Indexed as

AsthmaCommunity ParticipationModels, EconomicPatient ParticipationCost-Benefit AnalysisDecision MakingEconomics, MedicalHumansUncertainty

Identifiers

PMID41269490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.