Evidence map›Paper›PMID 41269484›Full record

SynthesisInternational journal of clinical oncology2026

Prognostic role of hand grip strength (HGS) on outcomes after gastrectomy for gastric cancer: a systematic review and meta-analysis.

Hsiao-Ling Chang, Chih-Ying Chien, Tzu-Ping Chen

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Hsiao-Ling ChangDepartment of General Surgery, Chang Gung Memorial Hospital, Keelung City, Taiwan.
Chih-Ying ChienDepartment of General Surgery, Chang Gung Memorial Hospital, Keelung City, Taiwan.
Tzu-Ping ChenDepartment of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital, No. 222, Mai-Chin Rd., Keelung City, 204, Taiwan. kkl3490@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) is a prevalent malignancy with a substantial impact on public health. Muscle quality and function may serve as predictors of poor clinical outcomes in GC. The aim of this updated meta-analysis was to evaluate the prognostic significance of hand grip strength (HGS) in patients undergoing gastrectomy for GC.

methodsA comprehensive literature search was conducted in PubMed, EMBASE, and Cochrane CENTRAL till August 2023, using keyword combinations of "hand grip strength", "gastric resection", and "gastrectomy". Eligible studies were those focused on outcomes of GC patients undergoing gastrectomy, with a comparison of preoperative HGS. The primary outcome was overall survival (OS); postoperative complications were assessed as a secondary outcome. Newcastle-Ottawa scale was used for quality assessment.

resultsNine studies involving 3,496 patients met our inclusion criteria, conducted primarily in China and Japan. A low HGS was significantly associated with worse OS (pooled adjusted hazard ratio [HR] = 2.29, 95% confidence interval [CI] 1.47-3.57) and increased postoperative complications (pooled adjusted odds ratio [OR] = 1.91, 95% CI 1.55-2.36). Sensitivity analysis confirmed the robustness of the results.

conclusionsThis meta-analysis highlights the prognostic relevance of preoperative HGS in GC patients undergoing gastrectomy. The findings strongly link low HGS to decreased OS and postoperative complications risk. This relationship suggests the potential of HGS as a valuable marker for a preoperative risk assessment and stratification.

Indexed as

GastrectomyHand StrengthPostoperative ComplicationsStomach NeoplasmsHumansPrognosisGastrectomyGastric cancer (GC)Hand grip strengthPrognosisSurvivalSystematic review and meta-analysis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.