Evidence map›Paper›PMID 41269479›Full record

ArticleJournal of gastrointestinal cancer2025

Association of Spirometric Lung Age with Survival Outcomes in Elderly Patients Undergoing Radical Surgery for Gastric Cancer.

Masayuki Urabe, Mami Suzuki, Takahiro Fukai, Yui Hasegawa, Emi Terai, Yoshitaka Kiya, Goki Morizono, Masaya Hiyoshi, Toshiyuki Watanabe, Yojiro Hashiguchi

Abstract read
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In one paragraph

Article in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Masayuki UrabeGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan. m-urabe.ju@omori.jrc.or.jp.ORCID http://orcid.org/0000-0002-5558-4184
Mami SuzukiGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Takahiro FukaiGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Yui HasegawaGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Emi TeraiGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Yoshitaka KiyaGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Goki MorizonoGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Masaya HiyoshiGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Toshiyuki WatanabeGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.
Yojiro HashiguchiGastrointestinal Surgery Division, Department of Surgery, Japanese Red Cross Omori Hospital, 4-30-1 Chuo, Ota-ku, Tokyo, 143-8527, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe proportion of elderly patients among those diagnosed with gastric cancer (GC) is increasing worldwide. Given that physiological reserves are often diminished in this population, reliable tools for preoperative risk stratification are essential to inform therapeutic decision-making. Lung age, a spirometry-derived clinical parameter, has been associated with postoperative outcomes in some malignancies; however, its relevance in GC remains unclear. This study retrospectively evaluated the prognostic significance of lung age in elderly GC patients undergoing curative gastrectomy.

methodsA total of 155 GC patients aged ≥ 70 years who underwent R0 gastrectomy were analyzed. The age gap (AG), defined as the difference between lung age and chronological age, was examined in relation to clinicopathological characteristics, postoperative complications, and survival outcomes.

resultsAG was significantly associated with postoperative complications. In univariate analyses, AG showed significant associations with overall survival (OS) and non-GC-related mortality, but not with cancer-specific survival. In multivariate analysis, AG was not an independent predictor of OS; however, it remained an independent predictor of non-GC-related death, whether analyzed as a dichotomous variable (hazard ratio [HR] 3.14, 95% confidence interval [CI] 1.33-7.38, p = 0.009) or as a continuous variable (HR 1.25 per 10-year increase, 95% CI 1.01-1.54, p = 0.036).

conclusionThe discrepancy between lung and chronological age may serve as a useful predictor of long-term outcomes, particularly non-GC-related mortality, in elderly patients undergoing curative gastrectomy. This metric may support risk stratification and inform surgical strategies in this vulnerable population.

Indexed as

GastrectomyLungPostoperative ComplicationsSpirometryStomach NeoplasmsAgedAged, 80 and overAge FactorsFemaleHumansMalePrognosisRetrospective StudiesSurvival RateElderlyGastrectomyGastric cancerPrognosisSpirometric lung age

Identifiers

PMID41269479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.