Evidence map›Paper›PMID 41269316›Full record

ArticleSurgical endoscopy2026

Flexible endoscopic treatment of internal hemorrhoids with versus without intravenous anesthesia: a retrospective study of 559 cases.

Xin Dai, Zhiyong Gu, Xiangliang Deng, Wenxian You, Tang Cao, Li Zhang, Hong He, Xiaofeng Chen, Jing Gu, Jin Xiao and 5 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xin DaiDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Zhiyong GuDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Xiangliang DengDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Wenxian YouDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Tang CaoDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Li ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Hong HeDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Xiaofeng ChenDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Jing GuDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Jin XiaoDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Ya HeDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Gangrong ZhaoDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Xiaohong TaoDepartment of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China.
Man Qiu *Department of Endoscopy Center, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China. 544010087@qq.com.
Xiaoyan Liang *Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.24 Shiyou Road, Yuzhong District, Chongqing, 400016, China. XiaoyanLiang2025@163.com.ORCID 0009-0009-2783-851X

Funding

National Natural Science Foundation of China No. 82273125Natural Science Foundation of Chongqing Municipality No. CSTB2022NSCQ-MSX0803)the High-level Medical Reserved Personnel Training Project of Chongqing No. 2023GDRC009
6 · The paper itself

Abstract

backgroundFlexible endoscopic therapies are effective for grade II-III internal hemorrhoids; however, the impact of intravenous anesthesia on clinical outcomes remains uncertain. This study compared the efficacy, safety, and cost-effectiveness of endoscopic treatment performed with versus without anesthesia.

methodsWe retrospectively analyzed 559 patients who underwent endoscopic rubber band ligation (ERBL) or polidocanol foam sclerotherapy (EPFS) from May 2023 to November 2024. Patients were stratified by anesthesia modality (intravenous propofol vs. no anesthesia). Primary outcomes included procedure time, retreatment rate, symptom improvement, postoperative discomfort, patient satisfaction, total cost, and cost acceptance. Subgroup analysis was performed for EPFS cases.

resultsBaseline characteristics were similar between groups. The anesthesia group had shorter procedure times (median 10.5 vs. 11.3 min, P = 0.036) and a lower retreatment rate (1.3% vs. 6.2%, P = 0.003). Rates of symptom improvement (83.1% vs. 82.7%, P = 0.940), postoperative discomfort, and patient satisfaction were comparable. Although the total treatment cost was higher in the anesthesia group (CNY 2,140.6 vs. 1,732.7, P < 0.001), cost acceptance remained high in both groups (85.8% vs. 91.4%, P = 0.173). Subgroup analysis of EPFS cases yielded consistent findings.

conclusionsFlexible endoscopic treatment for internal hemorrhoids is safe and effective regardless of anesthesia use. Intravenous anesthesia improves procedural efficiency and reduces retreatment rates without compromising symptom relief or satisfaction. These findings support individualized anesthesia strategies tailored to patient preferences and institutional resources.

Indexed as

Anesthesia, IntravenousEndoscopyHemorrhoidsSclerotherapyAdultAgedCost-Benefit AnalysisFemaleHumansLigationMaleMiddle AgedOperative TimePatient SatisfactionPolidocanolRetrospective StudiesPolidocanolSclerosing SolutionsAnesthesiaCost-effectivenessFlexible endoscopyInternal hemorrhoidsPolidocanolRubber band ligation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.