Evidence map›Paper›PMID 41269117›Full record

ArticleJournal of neurotrauma2026

Validation of A Wireless Telemetric Bladder Pressure Monitoring System in Traumatic Thoracic Spinal Cord Injury in Yucatan Minipigs.

Adam W Doelman, Jay Ethridge, Femke Streijger, Audrey Warner, Megan Webster, Avril Billingsley, Sid Gunamalai, Kitty So, Husain Kankroliwala, Martin S M Keung and 5 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adam W DoelmanInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Jay EthridgeInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Femke StreijgerInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Audrey WarnerInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Megan WebsterInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Avril BillingsleyInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Sid GunamalaiInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Kitty SoInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Husain KankroliwalaInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Martin S M KeungInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Neda ManouchehriInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Alex KavanaghInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.
Steve J A MajerusDepartment of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Margot S DamaserAdvanced Platform Technology Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Brian K KwonInternational Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada.

Funding

RRD VA IK6 RX003843
6 · The paper itself

Abstract

Neurogenic lower urinary tract dysfunction (NLUTD) is a major cause of morbidity and reduced quality of life after spinal cord injury (SCI). In pre-clinical research, small and large animal models such as rats, dogs, and minipigs have been used to investigate NLUTD through urodynamic studies (UDS) such as conventional filling cystometry. Although filling cystometry is currently considered the gold standard for bladder monitoring in pre-clinical research, this approach has several well-recognized limitations. The aim of this study was to develop and evaluate the feasibility of an implantable, radiotelemetric system for monitoring bladder pressure in a Yucatan minipig model of SCI. The transmitter was surgically implanted in the dome of the bladder and several UDS experiments were conducted to evaluate the system's effectiveness at measuring pressure compared to conventional UDS equipment. We observed a strong correlation and agreement between the transmural telemetry sensor and the UDS system. There was no significant difference between bladder compliance and baseline bladder pressure between the two sensor systems. However, the telemetry system recorded significantly lower voiding and non-voiding contraction pressure amplitudes as well as lower voiding threshold pressures and detrusor after-contraction measured with the telemetry system. The telemetry system appeared to be a reliable and accurate method for assessing bladder pressure and allowed for an evaluation of urodynamics in a pig model of SCI for several months. The application of this method could enable a more detailed in vivo evaluation of NLUTD after SCI and a better understanding of micturition behavior during natural-filling, ambulatory urodynamics.

Indexed as

Spinal Cord InjuriesTelemetryUrinary BladderUrinary Bladder, NeurogenicAnimalsDisease Models, AnimalFemalePressureSwineSwine, MiniatureThoracic VertebraeUrodynamicsWireless Technologyneurogenic bladderpigporcine modelspinal cord injurytelemetryurodynamics

Identifiers

PMID41269117
PMCPMC13482405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.