ArticleClinical transplantation2025
Utilization of Pediatric En Bloc Kidneys from Donation After Cardio-Circulatory Determination of Death: 15 Years of Experience.
Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Utilization of Pediatric En Bloc Kidneys from Donation After Cardio-Circulatory Determination of Death: 15 Years of Experience.Clinical transplantation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite the efforts by the Organ Procurement and Transplantation Network (OPTN) to improve utilization of organs from very small pediatric donors, en bloc kidney grafts are still disproportionately discarded. Although associated with increased technical complications, en bloc kidney transplants achieve excellent graft function and longevity. We present our single-center experience with en bloc kidney transplants in adult recipients and compare outcomes between donation after cardio-circulatory death (DCD) and brain death/death by neurologic criteria (BD/DNC) organs.
methodsRetrospective analysis was completed of all en bloc kidney transplants performed at a single-center academic transplant program, between 2008 and 2023. Two groups were defined according to the type of pediatric donor: DCD or BD/DNC. Demographic data, clinical variables, postoperative complications, and survival outcomes were compared between both groups.
resultsForty-two adult recipients received pediatric en bloc kidneys, 11 of these from DCD donors. The DGF rate was higher for DCD en bloc kidneys (27% vs. 16% for BD/DNC); however, this difference was not statistically significant. Nearly one third of patients required re-operation during the index transplant admission (28.6%). Four grafts were lost secondary to thrombosis -4(10%). Urological complications occurred in 9.5% of cases. Nevertheless, technical complications were not statistically different between both groups. Patient and graft survival rates were excellent in both groups. All recipients sustained serum creatinine values below 1 mg/dL beyond the first year post-transplant.
conclusionAlthough en bloc kidney transplantation of pediatric en bloc kidneys can be associated with greater rates of technical complications, these grafts can lead to excellent graft function and patient longevity. Diligent patient selection and an experienced surgical team are paramount to optimize the outcomes of en bloc kidney transplants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.