Evidence map›Paper›PMID 41268973›Full record

Trial reportIntegrative cancer therapies

Effectiveness of Shuanghuang Yangxue Decoction for Treating Cancer-Related Anemia With Serum Iron Deficiency in Lung Cancer Patients: A Randomized Clinical Trial.

Quan-Yao Li, Wen-Xiao Yang, Ying Lu, Dan Lin, Hui Mu, Qin Wang, Jia-Lin Yao, Hui Liu, Li-Qiu Yao, Xi Li and 5 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Quan-Yao LiShanghai Fourth People's Hospital Affiliated to Tongji University, China.ORCID 0000-0002-1496-9221
Wen-Xiao YangYueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China.
Ying LuShanghai (Medical School of Tongji University) Pengpu Xincun Community Health Care Center Internet Hospital, China.
Dan LinYueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China.
Hui MuThe First Affiliated Hospital of Naval Medical University, Shanghai, China.
Qin WangYueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China.ORCID 0000-0002-0851-7106
Jia-Lin YaoYueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China.
Hui LiuShanghai Fourth People's Hospital Affiliated to Tongji University, China.ORCID 0000-0002-9863-3345
Li-Qiu YaoJing'an District Hospital of Traditional Chinese Medicine, Shanghai, China.
Xi LiShanghai Fourth People's Hospital Affiliated to Tongji University, China.
Wen-Chao QiuShanghai Fourth People's Hospital Affiliated to Tongji University, China.
Pei-Pei XueShanghai Fourth People's Hospital Affiliated to Tongji University, China.
Chen QianShanghai Fourth People's Hospital Affiliated to Tongji University, China.
Ling XuYueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China.
Jun ShiShanghai Fourth People's Hospital Affiliated to Tongji University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy and safety of Shuanghuang Yangxue Decoction in treating lung cancer patients with cancer-related anemia (CRA) accompanied by serum iron deficiency.

methodOne hundred lung cancer patients with CRA and serum iron deficiency were included in this prospective randomized controlled study and randomly divided into control and treatment groups. The treatment group received Shuanghuang Yangxue Decoction plus ferrous succinate, while the control group received ferrous succinate alone. Related indicators were observed and recorded before and after treatment. Statistical analysis was performed using SPSS 26.0.

resultsThe effective correction rate of anemia in the treatment group was significantly higher than that in the control group (64 vs 34%,

conclusionShuanghuang Yangxue Decoction demonstrates superior efficacy compared to ferrous succinate alone in treating lung cancer CRA with serum iron deficiency. It effectively corrects anemia, increases serum iron levels, reduces inflammation, and is both safe and effective.

Indexed as

AnemiaAnemia, Iron-DeficiencyDrugs, Chinese HerbalLung NeoplasmsAdultAgedFemaleHemoglobinsHumansIronIron DeficienciesMaleMiddle AgedProspective StudiesTreatment OutcomeDrugs, Chinese HerbalHemoglobinsIroncancer-related anemialung cancerserum ironShuanghuang Yangxue Decoctiontraditional Chinese medicine

Identifiers

PMID41268973
PMCPMC12639223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.