Evidence map›Paper›PMID 41268627›Full record

ArticleAllergy2026

Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms.

Jean Bousquet, Bernardo Sousa-Pinto, Rafael José Vieira, Holger J Schünemann, Torsten Zuberbier, Antonio Bognanni, Alkis Togias, Boleslaw Samolinski, Arunas Valiulis, Sian Williams and 221 more

Abstract read
In one paragraph

Article in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Airborne Ragweed (Life (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

231 authors.

Jean BousquetInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-4061-4766
Bernardo Sousa-PintoMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Rafael José VieiraMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0003-1834-3055
Holger J SchünemannFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany.
Torsten ZuberbierInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-1466-8875
Antonio BognanniDepartment of Health Research Methods, Evidence, and Impact & Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-0128-903X
Alkis TogiasDivision of Allergy, Immunology, and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, Maryland, USA.
Boleslaw SamolinskiDepartment of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland.
Arunas ValiulisInstitute of Clinical Medicine and Institute of Health Sciences, Medical Faculty of Vilnius University, Vilnius, Lithuania.
Sian WilliamsInternational Primary Care Respiratory Group IPCRG, Edinburgh, UK.
Anna BedbrookARIA (Allergic Rhinitis and Its Impact on Asthma), Montpellier, France.
Wienczyslawa CzarlewskiARIA (Allergic Rhinitis and Its Impact on Asthma), Montpellier, France.
Maria Jose TorresAllergy Unit, Málaga Regional University Hospital of Málaga, Malaga University, ARADyAL, Malaga, Spain.ORCID 0000-0001-5228-471X
Mohamed H ShamjiNational Heart and Lung Institute (NHLI), Imperial College, and NIHR Imperial Biomedical Research Centre, London, UK.ORCID 0000-0003-3425-3463
Mário Morais-AlmeidaAllergy Center, CUF Descobertas Hospital, Lisbon, Portugal.ORCID 0000-0003-1837-2980
G Walter CanonicaDepartment of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy.ORCID 0000-0001-8467-2557
Leticia de Las VecillasDepartment of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.ORCID 0000-0003-4969-5678
Mark S DykewiczSection of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
Cristina Jacomelli"Respiriamo Insieme" Association, Asthma & Allergy Center, Padova, Italy.
Ludger KlimekDepartment of Otolaryngology, Head & Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany.ORCID 0000-0002-2455-0192
Lucas LeemannDepartment of Political Science, University of Zürich, Zürich, Switzerland.
Olga LourençoRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal.ORCID 0000-0002-8401-5976
Yuliia PalamarchukFinnish Meteorological Institute (FMI), Helsinki, Finland.
Nikolaos G PapadopoulosAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-4448-3468
Ana Margarida PereiraMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Marine SavouréBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.ORCID 0000-0003-3220-8175
Sanna K Toppila-SalmiDepartment of Allergy, Skin and Allergy Hospital, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0890-6686
Maria Teresa VenturaAllergy and Clinical Immunology, University of Bari Medical School, Bari, Italy.
Juan Jose Yepes-NuñezSchool of Medicine, Universidad de los Andes, Bogotá, DC, Colombia.
Alvaro A CruzFundaçao ProAR and (Faculdade de Medicina da), Universidade Federal da Bahia, Salvador, Bahia, Brazil.ORCID 0000-0002-7403-3871
Giorgio CiprandiCasa di Cura Villa Montallegro, Allergology Department, Genova, Italy.
Bilun GemiciogluDepartment of Pulmonary Diseases and Institute of Pulmonology and Tuberculosis, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.
Mattia GiovanniniDepartment of Health Sciences, University of Florence, Florence, Italy.ORCID 0000-0001-9568-6882
Brigita GradauskieneDepartment of Immunology and Allergology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Tuomas JarttiDepartment of Pediatrics and Adolescent Medicine, University of Turku, and Turku University Hospital, Turku, Finland.ORCID 0000-0003-2748-5362
Miloš JeseňákInstitute of Clinical Immunology and Medical Genetics, Department of Paediatrics and Adolescent Medicine, Department of Pulmonology and Phthisiology, Jessenius Faculty of Medicine, Martin, Slovakia.ORCID 0000-0001-7976-2523
Piotr KunaDivision of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland.
Violeta KvedarieneInstitute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Désirée E Larenas-LinnemannCenter of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico.
Amir H A LatiffAllergy & Immunology Centre, Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Yousser MohammadNational Center for Research in Chronic Respiratory Diseases, Collaborating With WHO-EMRO Tishreen University School of Medicine, Latakia, Syria.
Ken OhtaJapan Antituberculosis Association (JATA), Fukujuji Hospital, Tokyo, Japan.
Padukudru A MaheshDepartment of Respiratory Medicine, JSS Medical College, JSSAHER, Mysore, Karnataka, India.
Isabella Pali-SchöllDepartement of Biological Sciences and Pathophysiology, University of Veterinary Medicine, Vienna, Austria.
Oliver PfaarSection of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.ORCID 0000-0003-4374-9639
Frederico S RegateiroAllergy and Clinical Immunology Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Nicolas RochePneumologie, AP-HP Centre Université de Paris Cité, Hôpital Cochin, Paris, France.
Mikhail SofievFinnish Meteorological Institute (FMI), Helsinki, Finland.
Luís Taborda-BarataRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal.
Charlotte Suppli UlrikDepartment of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Copenhagen, Denmark.
Marylin Valentin RostanPediatrics, Allergy & Immunology, Latín American Society of Allergy, Asthma & Immunology (SLAAi), Montevideo, Uruguay.
Giovanni ViegiPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy.
Luo ZhangDepartment of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China.ORCID 0000-0002-0910-9884
Josep M AntóUniversitat Pompeu Fabra (UPF), Barcelona, Spain.
Tari HaahtelaSkin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0003-4757-2156
Ivan Cherrez-OjedaInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-1610-239X
Juan Carlos IvancevichServicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina.
Nikolai KhaltaevGlobal NCD Platform, Geneva, Switzerland.
Arzu YorganciogluDepartment of Pulmonary Diseases, Celal Bayar University, Faculty of Medicine, Manisa, Turkey.ORCID 0000-0002-4032-0944
Baharudin AbdullahDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Mona Al-AhmadMicrobiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Maryam Ali Al-NesfAdult Allergy and Immunology Division-Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0001-9354-0214
Rita AmaralMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0002-0233-830X
Julijana AsllaniDepartment of Internal Medicine, University of Medicine, Tirana, Albania.ORCID 0009-0003-1493-7101
Karl-C BergmannInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Jonathan A BernsteinDivision of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0002-3476-1196
Michael S BlaissDepartment of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Georgia, USA.
Fulvio BraidoDepartment of Internal Medicine (DIMI), University of Genoa, Genoa, Italy.
Paulo CamargosDepartment of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Pedro Carreiro-MartinsCHRC, LA-REAL, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisboa, Portugal.
Thomas CasaleDivision of Allergy/Immunology, University of South Florida, Tampa, Florida, USA.
Lorenzo CecchiSOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.ORCID 0000-0002-0658-2449
Alessandro G FiocchiAllergy, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.ORCID 0000-0002-2549-0523
Antonio F M GiulianoDepartment of Internal Medicine 'A. Murri' and Unit of Geriatric Immunoallergology, University of Bari Medical School, Bari, Italy.ORCID 0000-0002-9345-5156
George ChristoffFaculty of Public Health, Sofia Medical University, Sofia, Bulgaria.
Ieva CiruleLatvian Association of Allergists, University Children Hospital, Riga, Latvia.
Jaime Correia-de-SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0001-6459-7908
Elisio M CostaCINTESIS@RISE, Biochemistry Lab, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing, University of Porto, Porto, Portugal.
Stefano Del GiaccoDepartment of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology, University Hospital "Duilio Casula", University of Cagliari, Cagliari, Italy.ORCID 0000-0002-4517-1749
Philippe DevillierVIM Suresnes, UMR 0892, Pôle des Maladies des Voies Respiratoires, Hôpital Foch, Université Paris-Saclay, Suresnes, France.
Dejan DokicMedical Faculty Skopje, University Clinic of Pulmonology and Allergy, Skopje, Republic of Macedonia.
Elham HossnyPediatric Allergy, Immunology and Rheumatology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.
Tomohisa IinumaDepartment of Otorhinolaryngology, Chiba University, Chiba, Japan.ORCID 0000-0002-9940-5520
Carla IraniDepartment of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon.
Zhanat IspayevaDepartment of Allergology and Clinical Immunology, Kazakhstan Association of Allergology and Clinical Immunology, Kazakh National Medical University, Almaty, Kazakhstan.
Kaja JulgeInstitute of Clinical Medicine, Children's Clinic, Tartu University, Tartu, Estonia.
Igor KaidashevPoltava State Medical University, Immunology & Allergology Department, Poltava, Ukraine.
Kazi S BennoorDepartment of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh.
Helga KraxnerDepartment of Otorhinolaryngology, Head and Neck Surgery, Semmelweis University, Budapest, Hungary.
Inger KullDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6096-3771
Marek KulusDepartment of Pediatric Respiratory Diseases and Allergology, Medical University of Warsaw, Warsaw, Poland.
Maciej KupczykComenius University, Bratislava, Slovakia.
Andriy KurchenkoDepartment of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine.ORCID 0000-0001-6858-2025
Stefania La GruttaInstitute of Translational Pharmacology (IFT)-National Research Council (CNR), Palermo, Italy.
Neven MiculinicCroatian Pulmonary Society, Clinical Center for Pulmonary Diseases, Zagreb, Croatia.
Lan Le Thi TuyetAsthma, COPD Outpatient Care Unit, University Medical Center, Hô-Chi-Minh, Vietnam.
Michael MakrisAllergy Unit "D Kalogeromitros", 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.
Branislava MilenkovicClinic for Pulmonary Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Serbian Association for Asthma and COPD, Belgrade, Serbia.
Sang Min LeeDivision of Respiratory Disease and Allergy, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea.ORCID 0000-0002-9568-2096
Stephen MontefortDepartment of Medicine, Faculty of Medicine and Surgery, University of Malta, MSD, Msida, Malta.
André MoreiraEPIUnit-Institute of Public Health, University of Porto, and Laboratory for Integrative and Translational Research in Population Health (ITR), Porto, Portugal.
Joaquim MullolRhinology Unit & Smell Clínic, Department of Otorhinolaryngology, Hospital Clínic Barcelona, Universitat de Barcelona; FRCB-IDIBAPS; CIBERES, Barcelona, Spain.
Rachel NadifUniversité Paris-Saclay, UVSQ, Univ. Paris-Sud, Villejuif, France.ORCID 0000-0003-4938-9339
Alla NakonechnaImperial College Healthcare NHS Trust, London, UK.
Hugo E NeffenCenter of Allergy, Immunology and Respiratory Diseases, Santa Fe, Argentina.
Marek NiedoszytkoDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.ORCID 0000-0003-1089-1911
Dieudonné NyembueENT Department, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo.
Robyn O'HehirAllergy, Asthma and Clinical Immunology, Alfred Health, Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-3489-7595
Ismail OgulurSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Yoshitaka OkamotoChiba Rosai Hospital, ENT Department, Chiba, Japan.
Heidi OlzeDepartment of Otorhinolaryngology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Oscar PalomaresDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, Spain.ORCID 0000-0003-4516-0369
Petr PanznerDepartment of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic.ORCID 0000-0002-1291-450X
Vincenzo PatellaDivision of Allergy and Clinical Immunology, Department of Medicine, "Santa Maria della Speranza" Hospital, Battipaglia, Salerno, Italy.ORCID 0000-0001-5640-6446
Ruby PawankarDepartment of Pediatrics, Nippon Medical School, Tokyo, Japan.ORCID 0000-0002-3091-7237
Constantinos PitsiosMedical School, University of Cyprus, Nicosia, Cyprus.
Todor A PopovClinic of Occupational Diseases, University Hospital Sveti Ivan Rilski, Sofia, Bulgaria.
Francesca PuggioniIRCCS Humanitas Research Center, Personalized Medicine Asthma & Allergy, Rozzano, Milan, Italy.
Santiago QuirceDepartment of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Agné RamonaitéDepartment of Pulmonology and Allergology, Klaipeda National Hospital, Klaipeda, Lithuania.
Marysia RectoDivision of Adult and Pediatric Allergy and Immunology, University of the Philippines - Philippines General Hospital, Manila, Philippines.
Maria Susana Repka-RamirezDepartment of Allergy, Clinics Hospital, National University, San Lorenzo, Paraguay.ORCID 0000-0002-9570-1277
Graham RobertsFaculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0003-2252-1248
Karla Robles-VelascoCIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.ORCID 0000-0001-7780-1015
Menachem RottemDivision of Allergy, Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel.
Marianella SalapatasARIA, Asthma, Rhinitis, Immunology & Allergy Department, Athens, Greece.
Joaquin SastreAllergy Service, Fundacion Jimenez Diaz, Autonoma University of Madrid, CIBERES-ISCIII, Madrid, Spain.
Nicola ScichilonePROMISE Department, University of Palermo, Palermo, Italy.
Juan Carlos SisulAllergy & Asthma, Medical Director, CLINICA SISUL, FACAAI, SPAAI, Asuncion, Paraguay.
Dirceu SoléDivision of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
Manuel E Soto-MartinezDivision of Respiratory Medicine, Department of Pediatrics, Hospital Nacional de Niños, Universidad de Costa Rica, San Jose, Costa Rica.
Milan SovaDepartment of Respiratory Medicine and Tuberculosis, University Hospital, Brno, Czech Republic.
Pongsakorn TantilipikornDepartment of Otolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Ana Todo-BomImunoalergologia, Centro Hospitalar Universitário de Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Vladyslav TsarykSach's Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden.ORCID 0000-0002-5658-9737
Ioanna TsiligianniInternational Primary Care Respiratory Group IPCRG, Aberdeen, UK.
Marilyn Urrutia-PereiraDepartment of Medicine, Federal University of Pampa, Uruguaiana, Brazil.
Erkka ValovirtaDepartment of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland.
Eric Van GanseResearch on Healthcare Performance (RESHAPE), INSERM U1290, Pneumologie et Medicine Respiratoire, Groupement Hospitalier Nord, Hôpital de la Croix Rousse, Lyon, France.
Tuula VasankariFiLHA, Finnish Lung Health Association, Helsinki, Finland.
Dana WallaceNova Southeastern University, College of Allopathic Medicine, Fort Lauderdale, Florida, USA.
De Yun WangDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.ORCID 0000-0002-0909-2963
Margitta WormDivision of Allergy and Immunology, Department of Dermatology, Allergy and Venerology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-3449-1245
Osman M YusufThe Allergy and Asthma Institute, Allergy & Asthma Department, Islamabad, Pakistan.
Mihaela ZidarnUniversity Clinic of Respiratory and Allergic Diseases, Pulmonary & Allergy Department, Golnik, Slovenia.
Sara Gil-MataMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Manuel Marques-CruzMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Bassam MahboubPulmonary Department, Rashid Hospital, DUBAI Health, Dubai, UAE.
Ignacio J AnsoteguiDepartment of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain.
Antonino RomanoOasi Research Institute-IRCCS, Troina, Italy.
Maria Cristina ArtesaniAllergy, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.ORCID 0000-0003-2970-1591
Bruno BarretoDepartment of Allergy and Immunology, Para State University Center - CESUPA, Belém, Brazil.
Sven BeckerDepartment for Otorhinolaryngology, Head and Neck Surgery, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-1972-3797
Bianca BegheRespiratory Medicine, University of Modena & Reggio Emilia, Azienda Ospedaliera-Universitaria di Modena, Modena, Italy.
Jacques BouchardLaval University, Quebec City, Quebec, Canada.
Melisande Bourgoin-HeckDepartment of Pediatric Allergology, Armand Trousseau University Hospital, Sorbonne University, AP-HP, Paris, France.ORCID 0000-0001-6497-4830
Luisa BrussinoDepartment of Medical Sciences, University of Turin, Turin, Italy.
Roland BuhlDepartment of Pulmonary Medicine, Mainz University Hospital, Mainz, Germany.
Mario Calvo-GilPediatrics Department, Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile.
Victoria Cardona DahlAllergy Section, Department of Internal Medicine, Hospital Vall D'hebron, Barcelona, Spain.
José Antonio Castillo VizuetePneumology Department, Hospital Universitari Dexeus, Barcelona, Spain.
Denis CharpinClinique des Bronches, Allergie et Sommeil, Hôpital Nord, Marseille, France.
Niels H ChavannesNational eHealth Living Lab, Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
Marta ChełmińskaDepartment of Allergology, Medical University of Gdańsk, Gdańsk, Poland.
Lei ChengDepartment of Allergology and Department of Otorhinolaryngology, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Ekaterine ChkhartishviliAllergist, David Tvildiani Medical University, Tbilisi, Georgia.
Herberto Jose Chong-NetoAssociate Professor of Pediatrics, Division of Allergy and Immunology, Federal University of Parana, Curitiba, Brazil.
Deepa ChoudhuryPaediatric Allergy Clinic, Department of Dermatology, Amersham Hospital - NHS Hospital Trust, Amersham, UK.
Derek ChuDepartment of Health Research Methods, Evidence & Impact, McMaster University, Hamilton, Ontario, Canada.
Cemal CingiMedical Faculty, ENT Department, Eskisehir Osmangazi University, Eskisehir, Turkey.ORCID 0000-0003-3934-5092
Enrico CompalatiScientific & Medical Department, Lofarma S.p.A, Milan, Italy.
Biljana CvetkovskiWoolcock Institute of Medical Research, Sydney, Australia.
Jane Da SilvaAllergy Service, University Hospital Professor Polydoro Ernani de São Thiago (HU-UFSC/EBSERH), Florianópolis, Brazil.
Gennaro D'AmatoDivision of Respiratory and Allergic Diseases, High Specialty Hospital 'a Cardarelli', and Respiratory Allergy School of Specialization in Respiratory Diseases, Federico II University of Naples, Naples, Italy.ORCID 0000-0002-0503-9428
Janet DaviesCentre for Immunology and Infection Control, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia.
Danilo Di BonaDepartment of Medical and Surgical Sciences, School of Allergology and Clinical Immunology, University of Foggia, Foggia, Italy.
Maria V DimouAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.
Maria Do Ceu TeixeiraDr Agostinho Neto University Hospital, Epidemiology Department, Praia, Cabo Verde.
Maria DoulaptsiDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Crete, School of Medicine, Heraklion, Crete, Greece.ORCID 0000-0001-9011-0315
José Miguel Fuentes PérezAllergist, Private Practice, Mexico City, Mexico.ORCID 0000-0002-5378-3956
Radoslaw GawlikDepartment of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia in Katowice, Katowice, Poland.
Ozlem GokselDepartment of Pulmonary Medicine, Division of Immunology, Allergy and Asthma, Laboratory of Occupational and Environmental Respiratory Diseases, Faculty of Medicine, Ege University, EgeSAM (Ege University Translational Pulmonary Research, Center), Bornova, Türkiye.ORCID 0000-0003-1121-9967
Maximiliano R GómezFaculty of Health Sciences, Catholic University of Salta, Salta, Argentina.
Sandra N Gonzalez DiazAllergy and Clinical Immunology Centro Regional, Hospital Universitario, Universidad Autónoma de Nuevo Leon, Monterrey, Mexico.ORCID 0000-0002-3612-0042
Maia GotuaCenter of Allergy and Immunology, and Georgian Academy of Allergy, Asthma, and Clinical Immunology, Tbilisi, Georgia.
Christos GrigoreasDepartment of Allergy and Clinical Immunology, Air Force General Hospital, Athens, Greece.
Ineta GrisleRiga East University Hospital, Riga, Latvia.
Maria Antonieta GuzmanImmunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile.
Rachel House TanQuality Use of Research Medicines Group, Woolcock Institute of Medical Research, Macquarie Park NSW, Australia.
Michael HylandFaculty of Health, University of Plymouth, Plymouth, UK.
Despo IerodiakonouDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Aspasia KaraveliaOtolaryngology Department, General Hospital of Kalamata, Kalamata, Greece.
Marta KisielDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Mitja KosnikUniversity Clinic of Respiratory and Allergic Diseases, Pulmonary & Allergy Department, Golnik, Slovenia.ORCID 0000-0002-4701-7374
Vicky KritikosClinical Management Group, Woolcock Institute of Medical Research, Sydney, Australia.ORCID 0000-0003-3955-0002
Carlo LombardiDepartmental Unit of Allergology, Clinical Immunology & Pneumology, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Matteo MartiniAllergy Unit, Department of Internal Medicine, University Hospital AOU delle Marche, Ancona, Italy.ORCID 0000-0001-9873-9695
Cem MeçoDepartment of Otorhinolaryngology, Head and Neck Surgery, Ankara University Medical School, Ankara, Turkey.
Eris MesonjesiAllergy and Clinical Immunology Department, University Hospital Center "Mother Teresa", Tirana, Albania.
Florin MihaltanUMF-University of Medicine and Pharmacy 'Carol Davila', Pneumology Department, National Institute of Pneumology 'Marius Nasta', Bucharest, Romania.
Marcin MoniuszkoDepartment of Allergology and Internal Medicine, Medical University of Bialystok, Byalistok, Poland.
Robert NaclerioDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
Sophia NeisingerInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Michal OrdakDepartment of Pharmacotherapy and Pharmaceutical Care, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0001-5652-4397
Giovanni PaolettiDepartment of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy.ORCID 0000-0003-3953-9225
Edgar Arturo Perdomo-FloresOtorhinolaryngology and Neck Surgery Unit, San Juan de Dios National Hospital, San Miguel, El Salvador.
Nhan Pham-ThiEcole Polytechnique de Palaiseau, Palaiseau, France.
Emmanuel ProkopakisDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Crete, School of Medicine, Heraklion, Crete, Greece.
Daniela Rivero YeverinoServicio de Alergia e Inmunología clínica, Hospital Universitario de Puebla, Puebla, México.
Giovanni RollaDepartment of Medical Sciences, University of Turin, Turin, Italy.
Jan RomantowskiDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Philip W RouadiDepartment of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.ORCID 0000-0002-5365-9568
Maia RukhadzeCenter Allergy & Immunology and Geomedi Teaching University, Faculty of Medicine, Tbilisi, Georgia.
Daiju SakuraiDepartment of Otorhinolaryngology, Head and Neck Surgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Laila SalamehMohammed Bin Rashid University (MBRU), Dubai Health, Dubai, UAE.
Faradiba Serpa SarquisAsthma Reference Center-School of Medicine of Santa Casa de Misericórdia of Vitória, Espírito Santo, Brazil.
Tanja Soklic KosakORL SOKLIC KOSAK, Ljubljana, Slovenia.ORCID 0000-0002-9326-7606
Michael SoykaOtolaryngology-HNS, University of Zurich, University Hospital of Zurich, Zurich, Switzerland.ORCID 0000-0003-4179-4989
Olga SozinovaHead of Laboratory of Atmospheric Processes and Aerobiology, University of Latvia, Riga, Latvia.ORCID 0000-0001-9725-7790
Krzysztof SpecjalskiDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Vesna Tomic-SpiricClinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia.
Martina VachovaDepartment of Immunology and Allergology, University Hospital and Faculty of Medicine in Pilsen, Czech Republic.
Marianne van HageDepartment of Medicine Solna, Division of Immunology and Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-3091-1596
Ilgim Vardaloglu KoyuncuDepartment of Chest Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.
Pakit VichyanondDivision of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand.
Martin WagenmannDepartment of Otorhinolaryngology, Heinrich Heine University Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Düsseldorf, Germany.ORCID 0000-0002-9734-0241
Fanny Wai San KoDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Pascal WerminghausENT and Allergology, Düsseldorf, Germany.
Vicky Paraskevi XepapadakiAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.
Yi-Kui XiangInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-3432-6837
João A FonsecaMEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.

Funding

ARIA (Allergic Rhinitis and its Impact on Asthma), Montpellier, FranceCINTESIS@RISE, Porto, PortugalFraunhofer-Institut für Translationale Medizin und PharmakologieWorld Health Organization 001
6 · The paper itself

Abstract

The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA-ARIA 2024-2025-in collaboration with EAACI is currently being developed, focusing on the management of allergic rhinitis. ARIA 2024-2025 follows the GRADE framework and is endorsed by the European Academy of Allergy and Clinical Immunology (EAACI). A set of approaches has been used to develop guideline questions, including surveying key opinion leaders and using artificial intelligence (AI)-based tools to analyse web searches on allergic rhinitis and to generate questions. Each prioritised guideline question is assessed through an Evidence-to-Decision (EtD) framework. EtDs support the systematic and transparent formulation of recommendations, comprising 12 criteria for which the best available evidence should be sought. In the context of ARIA-EAACI 2024-2025, such evidence is derived not only from randomised controlled trials but also-among others-from patient-generated data sources that better reflect the affected individuals' perspectives. Moreover, ARIA-EAACI 2024-2025 incorporates evidence on planetary health. Developed guideline recommendations will support the creation of digitalised decision algorithms and care pathways. This paper describes the methodology used to develop the person-centred, digitally enabled and AI-assisted ARIA-EAACI 2024-2025. Among others, it describes (i) the development and prioritisation of guideline questions, (ii) sources of evidence for EtDs and (iii) the development of digitalised decision algorithms and care pathways.

Indexed as

AlgorithmsAsthmaDecision Making, SharedPractice Guidelines as TopicRhinitis, AllergicClinical Decision-MakingDisease ManagementEvidence-Based MedicineHumansallergic rhinitisasthmaENT (rhinitis, sinusitis, nasal polyps…)guidelines

Identifiers

PMID41268627
PMCPMC12862529

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