Evidence map›Paper›PMID 41268564›Full record

ReviewFrontiers in immunology2025

Mechanisms of aging in the cardiovascular system: challenges and opportunities.

Xiaoying Zhao, Xinyue Yang, Yumeng Lin, Ruolan Lei, Wei Ding, Xinying He, Ying Cao, Dechou Zhang, Ping Liu, Meirou Liang and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoying Zhao *Department of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Xinyue Yang *Department of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Yumeng Lin *Health Management Center, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, China.
Ruolan LeiDepartment of Nutrition, The First People's Hospital of Zigong, Zigong, China.
Wei DingThe First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Xinying HeDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Ying CaoDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Dechou ZhangDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Ping LiuDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Meirou LiangThe First Clinical Medical College of Shaanxi University of Chinese Medicine, Xi'an, China.
Zhongyu HanDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Yu JiangDepartment of Gerontology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) pose a significant threat to the health of the elderly population. As the global population ages and medical management remains imperfect, reducing the medical burden of CVDs is of great importance. Aging is a complex process that contributes to the development and progression of CVDs through various mechanisms. The manuscript reviews the mechanisms of aging and their impact on the cardiovascular system. We explore the role of aging in the cardiac microenvironment, highlighting the changes that occur in the heart's cellular and molecular landscape as a result of the aging process.

Indexed as

AgingCardiovascular DiseasesCardiovascular SystemAnimalsHumansagingcardiac agingcardiac microenvironmentinflammationtherapy

Identifiers

PMID41268564
PMCPMC12626939

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.