Evidence map›Paper›PMID 41268435›Full record

ArticleRespirology case reports2025

A Case of Mucous Gland Adenoma of the Lung Representing NKX3.1-Positive Lung Tumour Spectrum.

Koichiro Ishii, Takao Nakanishi, Taishi Adachi, Hideki Motoyama, Maki Kanzawa, Mitsugu Omasa

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Koichiro IshiiDepartment of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.ORCID https://orcid.org/0009-0005-6604-027X
Takao NakanishiDepartment of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.ORCID https://orcid.org/0000-0003-2275-5896
Taishi AdachiDepartment of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.
Hideki MotoyamaDepartment of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.
Maki KanzawaDepartment of Diagnostic Pathology Kobe City Nishi-Kobe Medical Center Kobe Japan.
Mitsugu OmasaDepartment of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucous gland adenoma (MGA) is a rare, benign lung tumour. Recently, NKX3.1 immunohistochemistry was reported to be a diagnostic marker for distinguishing MGA from other mucinous tumours. A 60-year-old male with a 20-year history of a tumor-like lesion, primarily composed of mucus in the left lingual region. While the lesion was being monitored, its size gradually increased. We then performed a segmentectomy of the lingula. Postoperative pathological examination showed that the tumour had a tubulopapillary structure. The tumour cells were columnar with slight atypia, diffusely positive for NKX3.1 and were diagnosed as MGA. No recurrence was found after 6 months of postoperative follow-up, and the sputum count had markedly decreased. This case report aids in elucidating the pathogenesis of MGA and NKX3.1-positive lung tumours.

Indexed as

benign lung tumourcellular atypiamucous gland adenomaNKX3.1seromucinous bronchial glands

Identifiers

PMID41268435
PMCPMC12626762

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