Evidence map›Paper›PMID 41268432›Full record

ArticleJournal of surgical case reports2025

Management of spontaneous atraumatic splenic rupture in the setting of anticoagulation: case report and literature review.

Christina Regelsberger-Alvarez, Scarlett B Hao, Sarah K Struble, Kieran J Ved

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina Regelsberger-AlvarezDivision of Trauma and Acute Care Surgery, Department of Surgery, East Carolina University, 600 Moye Boulevard, Greenville, NC 27834, United States.
Scarlett B HaoColon and Rectal Surgery, Norton Surgical Specialists - Colorectal Health, 3999 Dutchmans Lane, Suite 2E, Louisville, KY 40207, United States.ORCID https://orcid.org/0000-0002-6156-9327
Sarah K StrubleDivision of General Surgery, Department of Surgery, East Carolina University, 600 Moye Boulevard, Greenville, NC 27834, United States.
Kieran J VedDepartment of Emergency Medicine, UNC Health Southeastern, 300 W. 27th St. Lumberton, NC 28358, United States.ORCID https://orcid.org/0009-0000-5187-9789

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old male with a history of atrial fibrillation on apixaban with no recent history of trauma presented with acute onset abdominal pain and hypotension with no identified precipitating event. Intraabdominal free fluid was noted on bedside ultrasound, and computed tomography angiography of the abdomen showed splenic rupture. Anticoagulation was reversed with prothrombin complex, and he was taken to the operating room for emergent splenectomy. Spontaneous splenic rupture is uncommon, but as with traumatic splenic injuries, it may be managed operatively or non-operatively. In patients on therapeutic anticoagulation, reversal agents should be considered. Spontaneous splenic rupture may lead to life-threatening hemorrhage, particularly for patients on therapeutic anticoagulation. This case highlights the importance of timely diagnosis and operative intervention as well as the role of anticoagulation reversal for these patients.

Indexed as

anticoagulationsplenectomyspontaneous splenic rupture

Identifiers

PMID41268432
PMCPMC12628189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.