ArticleFrontiers in public health2025
Prevalence of primary HIV-1 drug resistance among antiretroviral-naïve individuals in Togo in 2023: a national study.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Advancements in development of novel class of HIV protease inhibitors.Annals of medicine · 2026Review
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Authors and funding
16 authors.
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Abstract
Monitoring pre-treatment drug resistance is a priority to assess the emergence of HIV resistance to antiretrovirals, especially in countries where the transition from dolutegravir-based regimens is already effective on a large scale. The aim of this study was to estimate the prevalence of resistance mutations to different classes of antiretrovirals (ARVs) in HIV-1-naïve persons in Togo in 2023. A cross-sectional study was conducted in 30 HIV care centers for people living with HIV in Togo between March and August 2023. Persons newly diagnosed with HIV-1, aged 18 and over and naïve to any ART with a viral load ≥ 6500.00 copies/ml were included for genotypic resistance testing for protease (PR), reverse transcriptase (RT) and integrase (IN) genes using Next-generation sequencing. Mutations were interpreted using the updated Stanford HIVDB and ANRS algorithms after genotypic testing for protease, reverse transcriptase and integrase resistance. Among 376 enrolled
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