Evidence map›Paper›PMID 41268341›Full record

ArticleBioactive materials2025

Biomimetic aligned bacterial cellulose dressing containing polydeoxyribonucleotide for promoting wound healing.

Xiaoqian Zhu, Fan Liu, Tuwei Jin, Hongkun Chen, Sung-Min Chung, Cen Chen, In-Seop Lee

Abstract read
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoqian ZhuCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, PR China.
Fan LiuDepartment of Orthodontics, School of Stomatology, China Medical University, Shenyang, 110002, PR China.
Tuwei JinCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, PR China.
Hongkun ChenCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, PR China.
Sung-Min ChungBiomaterials R&D Center, Genoss Co., Ltd., Suwon, 443270, Republic of Korea.
Cen ChenCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, PR China.
In-Seop LeeInstitute of Human Materials, Suwon, 16514, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic or non-healing wounds present a significant challenge in daily life, leading to increased interest in the design of wound dressings with enhanced healing capabilities. In this study, a bacterial cellulose (BC) membrane with an aligned structure was developed to guide cell migration and collagen orientation, serving as the primary component of the wound dressing. Polydeoxyribonucleotide (PDRN), a nucleic acid agent known for its excellent tissue-regenerative effect, were loaded into the aligned BC membrane. The obtained composite material (PDRN@BC aligned membrane) demonstrated aligned structure, high hydrophilicity, favorable air permeability, good mechanical properties, and sustained release of PDRN. The as-prepared membrane promoted cell spreading, proliferation and migration of L929 fibroblast

Indexed as

Bacterial celluloseFiber alignmentPolydeoxyribonucleotideWound healing

Identifiers

PMID41268341
PMCPMC12628134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.