Evidence map›Paper›PMID 41268314›Full record

ArticleJournal of ginseng research2025

Effects of white ginseng on reducing stress and tension by enhancing default mode network connectivity: A randomized, double-blinded placebo-controlled clinical trial.

Youngeun Shim, Young-Seob Lee, Yejin Kim, Seung Eun Lee, Chaewon Suh, Eunji Ha, Yoonji Joo, Hyeonji Lee, Suji Lee, Woo Cheol Shin and 3 more

Abstract read
In one paragraph

Article in Journal of ginseng research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Advances in Research onInternational journal of molecular sciences · 2026
    Review
  2. Review
  3. Ginsenosides fromJournal of ginseng research · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Youngeun ShimEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Young-Seob LeeDepartment of Herbal Crop Research, National Institute of Horticultural Herbal Science, Rural Development Administration, Eumseong, 27709, Republic of Korea.
Yejin KimEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Seung Eun LeeDepartment of Herbal Crop Research, National Institute of Horticultural Herbal Science, Rural Development Administration, Eumseong, 27709, Republic of Korea.
Chaewon SuhEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Eunji HaEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Yoonji JooEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Hyeonji LeeEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Suji LeeDivision of Psychology and Cognitive Science, Seoul Women's University, Seoul, 01797, Republic of Korea.
Woo Cheol ShinBK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Sujung YoonEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
In Kyoon LyooEwha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Dae Young LeeBK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent research has increasingly focused on the potential role of white ginseng ( Methods: A total of 86 participants reporting stress-related symptoms were randomized to receive either PGC (n = 42) or a placebo (n = 44). Stress levels were assessed using a composite stress index, which was derived from self-reported measures, skin conductance response, and heart rate variability, at baseline, week 6, and week 12. Additionally, resting-state functional magnetic resonance imaging was conducted at the same time points. Results: PGC treatment resulted in a statistically significant reduction in the composite stress index compared to placebo ( Conclusion: The findings of this study suggest that PGC has the potential to mitigate stress and tension, potentially through the modulation of DMN functional connectivity.

Indexed as

Default mode networkFunctional connectivityStress reductionWhite ginseng

Identifiers

PMID41268314
PMCPMC12629729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.