Evidence map›Paper›PMID 41268280›Full record

ArticleAmerican journal of translational research2025

A retrospective comparative study of helium-neon laser combined with ultrasonic debridement in improving healing of chronic non-healing wounds.

Wanjun Yang, Lei Zhao, Hongwei Zhu, Siyuan Chen, Canyu Yang

Abstract read
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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Wanjun YangDepoartment of Dermatology, Panzhihua Central Hospital Panzhihua 617000, Sichuan, China.
Lei ZhaoDepoartment of Dermatology, Panzhihua Central Hospital Panzhihua 617000, Sichuan, China.
Hongwei ZhuDepoartment of Dermatology, Panzhihua Central Hospital Panzhihua 617000, Sichuan, China.
Siyuan ChenQueen Mary College, Department of Medicine, Qianhu Campus, Nanchang University Nanchang 330006, Jiangxi, China.
Canyu YangQueen Mary College, Department of Medicine, Qianhu Campus, Nanchang University Nanchang 330006, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical value of ultrasonic debridement alone, helium-neon (He-Ne) laser therapy alone, and their combined use in the treatment of chronic non-healing wounds.

methodsA total of 272 patients with chronic non-healing wounds treated at Panzhihua Central Hospital between October 2023 and December 2024 were retrospectively selected and assigned to three groups according to treatment modality: a combined group (n=90, He-Ne laser and ultrasonic debridement), an ultrasonic debridement group (n=95, ultrasonic debridement alone), and a He-Ne laser group (n=87, He-Ne laser alone). Clinical indicators, including wound healing, Pressure Ulcer Scale for Healing (PUSH) scores, microbiological parameters, and visual analog scale (VAS) scores were assessed before treatment and at 4, 8, and 12 weeks after treatment. Adverse reactions during treatment and recurrence rates within six-month of follow-up were collected.

resultsThe combined group achieved better efficacy compared with the single-treatment groups at all assessment time points. At 12 weeks after treatment, the combined group demonstrated higher complete healing rates than the single-treatment groups (

conclusionThe combined application of He-Ne laser therapy and ultrasonic debridement provides significant advantages in managing chronic non-healing wounds. This approach effectively promotes wound healing, enhances bacterial clearance, alleviates pain, shortens treatment cycles, lowers recurrence risk, and reduces treatment-related adverse reactions.

Indexed as

chronic non-healing woundscombined treatmentHe-Ne laserUltrasonic debridement

Identifiers

PMID41268280
PMCPMC12628234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.