ArticleAmerican journal of translational research2025
Predictive value of nutritional status for delayed healing after open fracture of the extremities in the elderly: construction of a nomogram model.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Performance of prediction models for delayed union and nonunion after fracture: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Review
- A multi-parameter ultrasound prediction model for nutrition-associated skin failure in hospitalized elderly patients: a prospective cohort study protocol.BMC geriatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association between preoperative nutritional indicators and postoperative fracture healing outcomes in elderly individuals.
methodsA retrospective analysis was conducted on 221 patients aged 60 years or older who underwent surgery for open extremity fractures at Shanghai Sixth People's Hospital between March 2021 and November 2024. Patients were stratified into normal healing (n=139) and delayed healing (n=82) groups based on radiographic criteria at four months postoperatively. Preoperative nutritional status was assessed using BMI, albumin, prealbumin, hemoglobin, lymphocyte count, Mini Nutritional Assessment (MNA), Nutritional Risk Screening 2002 (NRS-2002), and Subjective Global Assessment (SGA). Statistical analyses included chi-square tests, independent samples t-tests, logistic regression, and receiver operating characteristic (ROC) curve analyses.
resultsThe incidence of delayed healing was 37.1%. BMI, albumin (P=0.006), prealbumin (P=0.014), hemoglobin (P=0.042), and MNA scores (P=0.029), and NRS-2002 scores (P=0.004) were significantly associated with healing outcome. Multivariate logistic regression identified BMI (OR=0.729, P=0.006), albumin (OR=0.933, P=0.040), prealbumin (OR=0.979, P=0.015), MNA (OR=0.933, P=0.020), and SGA (OR=0.478, P=0.033) as independent protective factors for normal healing; while lymphocyte count and NRS-2002 were independent risk factors. ROC analysis showed high predictive value for delayed healing using these markers (AUC=0.964), and an integrated nomogram model achieved high discriminative ability.
conclusionPreoperative nutritional status, as evidenced by BMI, serum protein markers, and validated nutritional assessment scales, was significantly associated with postoperative fracture healing outcomes in elderly patients following open extremity fracture surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.