ArticleAmerican journal of translational research2025
Tetraplegia after atrial fibrillation ablation: a rare complication due to unrecognized cervical ossification of the posterior longitudinal ligament.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Catheter ablation is widely regarded as a safe and effective treatment for atrial fibrillation (AF). However, rare but severe complications may occur, particularly in patients with undiagnosed structural abnormalities. A 60-year-old man with paroxysmal AF developed complete tetraplegia following catheter ablation under moderate sedation. The procedure was uneventful; however, the patient immediately developed profound quadriparesis. An urgent cervical spine Magnetic Resonance Imaging revealed extensive mixed-type ossification of the posterior longitudinal ligament (OPLL) from C2 to T2 with severe spinal cord compression at C5 and intramedullary high-signal changes, indicating acute compressive myelopathy. Despite emergent decompressive laminectomy and fusion, the patient remained tetraplegic with American Spinal Injury Association grade A status. No neurological improvement was noted at the two-year follow-up. This case underscores the importance of recognizing occult cervical spine pathology, such as OPLL, as a risk factor for spinal cord injury during procedures involving neck positioning or sedation. Preprocedural cervical imaging is warranted in high-risk individuals to prevent catastrophic outcomes. To the best of our knowledge, this is the first reported case of irreversible tetraplegia due to undiagnosed OPLL following AF ablation.
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