ArticleAmerican journal of translational research2025
Effects of Yixin Da cervical double-lumen balloon dilatation combined with low-dose oxytocin on cervical maturation in term labor induction.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate the efficacy of the Yixin Da cervical double-lumen balloon dilatation combined with low-dose oxytocin in promoting cervical ripening during term labor induction.
methodsThis retrospective study analyzed 100 full-term labor induction cases at Beijing Luhe Hospital Affiliated to Capital Medical University between January 2022 and December 2023. Participants were divided into a control group (n=50), receiving low-dose oxytocin, and a study group (n=50), receiving the Yixin Da cervical double-lumen balloon catheter combined with low-dose oxytocin. The outcomes assessed included cervical ripening efficacy, induction duration, Bishop score changes, labor progression, Endothelin-1 (ET-1) and Prostaglandin E2 (PGE2) levels, and the incidence of adverse events.
resultsThe study group exhibited higher cervical ripening efficacy (98.00% vs. 84.00%, P<0.05), a shorter induction-to-labor time, and reduced labor stages (P<0.05). VAS pain scores were lower (P<0.05), and Bishop scores showed greater improvement in the study group (P<0.05). Postpartum hemorrhage rates were lower in the study group (P<0.05). ET-1 and PGE2 levels post-treatment were significantly higher in the study group compared to the control group, despite no pretreatment differences (P<0.05). The incidence of adverse events was lower in the study group (2.00% vs. 16.00%, P<0.05), and patient satisfaction was higher (P<0.05).
conclusionThe combination of the Yixin Da balloon with low-dose oxytocin enhances cervical ripening, shortens labor duration, and reduces complications, demonstrating superior efficacy.
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