Evidence map›Paper›PMID 41268231›Full record

ArticleAmerican journal of translational research2025

Combined effects of tranexamic acid and platelet-rich plasma in the arthroscopic treatment of femoroacetabular impingement.

Gejun Liu, Litao Yan, Lei Zhang, Zhecheng Jiang, Huan Li, Fan Zhao

Abstract read
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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gejun LiuDepartment of Orthopedics, Shanghai Tenth People's Hospital, Tongji University Shanghai, China.
Litao YanDepartment of Articular Orthopaedics, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University Changzhou, Jiangsu, China.
Lei ZhangBeigang Street Community Health Service Center Changzhou, Jiangsu, China.
Zhecheng JiangDepartment of Articular Orthopaedics, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University Changzhou, Jiangsu, China.
Huan LiDepartment of Articular Orthopaedics, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University Changzhou, Jiangsu, China.
Fan ZhaoDepartment of Orthopaedics, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University Changzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the combined effects of tranexamic acid (TXA) and platelet-rich plasma (PRP) in the arthroscopic treatment of femoroacetabular impingement (FAI).

methodsA total of 78 FAI patients were included. In the PRP group (n=36), PRP monotherapy was administered, while the TXA + PRP group (n=42) received both TXA and PRP. We performed comparative analyses on clinical outcomes, surgical metrics, coagulation tests, computed tomography (CT) measurements, Visual Analogue Scale (VAS) pain severity scores, hip joint functionality, serum inflammatory biomarkers, and quality of life.

resultsThe combination of TXA and PRP demonstrated superior outcomes compared to PRP alone, with higher overall efficacy, improved arthroscopic visual clarity, reduced intraoperative and total blood loss, and shorter hospital stays (all P<0.05). Additionally, the TXA + PRP group showed a significant reduction in α and center-edge angles at the 12-months postoperative follow-up compared to both baseline and the PRP group (all P<0.05). Furthermore, significant improvements were observed in coagulation function, pain relief, hip joint function, quality of life, and a more effective reduction in serum inflammation (all P<0.05).

conclusionCo-administration of TXA and PRP is highly effective in the management of FAI through hip arthroscopy.

Indexed as

clinical efficacyfemoroacetabular impingementHip arthroscopyhip joint functionplatelet-rich plasmatranexamic acid

Identifiers

PMID41268231
PMCPMC12628195

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.