Evidence map›Paper›PMID 41268202›Full record

ArticleClinical, cosmetic and investigational dermatology2025

The Quantification of Terminal Hair by Digital Microscopy: Advancements Towards a More Objective Diagnosis of Hirsutism.

Romy W P M De Kroon, Martin Den Heijer, Sharon J Haarman, Rudolf M Verdaasdonk, Annemieke C Heijboer

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Quantitative effects of sex hormones on hair growth and patient satisfaction.The Journal of clinical endocrinology and metabolism · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Romy W P M De KroonEndocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-4912-7814
Martin Den HeijerAmsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, the Netherlands.
Sharon J HaarmanEndocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.
Rudolf M VerdaasdonkTechMed Center, Department of Health Technology Implementation, University of Twente, Enschede, the Netherlands.
Annemieke C HeijboerEndocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-6712-9955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The modified Ferriman-Gallwey score, currently used to clinically evaluate and quantify excessive hair growth in women with hirsutism, has limitations because of its subjective nature. Therefore, we aim to investigate whether we could quantify terminal hairs on the output of a digital microscope camera to improve the clinical evaluation of hirsutism. Patients and Methods: This feasibility cross-sectional study included 20 healthy men and 15 healthy women. Two independent researchers used a digital microscope camera to obtain photos of the upper lip and chin in all participants. The hair thickness (when ≥ 60 µm), number of terminal hairs and hair color were determined to indicate mean differences between men and women by an independent Results: The mean (standard deviation) number of terminal hairs on the upper lip was 27 (15) in men and 0 (1) in women. On the chin, men had a mean (standard deviation) of 29 (18) terminal hairs, compared to 0 (0) in women. This corresponds to mean differences of 27 hairs (range: 19-34) on the upper lip and 28 hairs (range: 19-39) on the chin between men and women. Minimal inter-observer variability was observed, particularly in visible light analyses (intraclass correlation coefficient: 0.998). Conclusion: Digital microscopy with visible light may contribute to a more objective method for diagnosing hirsutism by the quantification of terminal hair. Future studies should focus on the applicability of this new method in women with hirsutism.

Indexed as

androgensdigital microscopyFerriman-Gallwey scorehirsutismhyperandrogenismterminal hair

Identifiers

PMID41268202
PMCPMC12629248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.