Evidence map›Paper›PMID 41268146›Full record

ArticleJournal of health economics and outcomes research2025

Performance of the Experimental EuroQol Toddler and Infant Populations (EQ-TIPS) and PedsQL in Infants and Toddlers with a Health Condition.

Janine Verstraete, Marco Zampoli, Alan Davidson, Marc Hendricks, Helder de Quintal, Yasmin Goga, Jo M Wilmshurst, Alvin Ndondo, Gillian Riordan, Ronalda De Lacy and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of health economics and outcomes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Impact of inactivated influenza vaccination on health-related quality of life for young children using Japanese experimental EuroQol toddler and infant populations (EQ-TIPS) v2.0.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Janine VerstraetePaediatrics and Child Health Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0002-1148-4747
Marco ZampoliDivision of Pulmonology, Department of Paediatrics and Child Health Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0002-6899-6137
Alan DavidsonDivision of Haematology and Oncology Red Cross War Memorial Children's Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-4646-4332
Marc HendricksDivision of Haematology and Oncology, Department of Paediatrics and Child Health Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0002-3636-0994
Helder de QuintalRed Cross War Memorial Children's Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-3796-4420
Yasmin GogaDivision of Haematology and Oncology, Department of Paediatrics and Child Health, Faculty of Health Sciences University of Cape Town, South Africa.
Jo M WilmshurstDepartment of Paediatric Neurology Red Cross War Memorial Children's Hospital, Cape Town, South A.ORCID https://orcid.org/0000-0001-7328-1796
Alvin NdondoNeuroscience Institute, University of Cape Town, South Africa.
Gillian RiordanNeuroscience Institute, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0003-2698-9948
Ronalda De LacyRed Cross War Memorial Children's Hospital, Cape Town, South Africa.
Mignon McCulloghRed Cross War Memorial Children's Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-2876-4785
Deveshni ReddyRed Cross War Memorial Children's Hospital.ORCID https://orcid.org/0000-0001-5575-7586
Lasse HerdienDepartment of Paediatrics and Child Health Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5961-8962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Health-related quality of life measurement in infants and toddlers is increasingly important, but generic preference-weighted instruments lack evidence. This study compared the experimental EuroQol Toddler and Infant Populations (EQ-TIPS) and PedsQL in children 0 to 4 years. Methods: EQ-TIPS-3L v2.0 and PedsQL response distributions were compared by frequency. Item and dimension/summary score associations were computed using Pearson and intra-class correlation coefficient. Age and severity groups (EQ VAS ≥80) were compared with Mann-Whitney U tests. Results: Cross-sectional data from 260 children were analyzed: 0 to 24 months (n = 111) and 2 to 4 years (n = 149). Most caregivers were mothers, spending significantly more time (≥10 hours) with younger children χ2 = 18.12, Conclusion: Both measures showed similar response distributions despite different time frames and response scales. EQ-TIPS-3L eating and pain reported high problems, with eating strongly associated only with PedsQL physical symptoms. The 2- to 4-year PedsQL version had many missing school functioning items; the 13- to 24-month PedsQL may suit older 2- to 4-year-olds better. Low association between PedsQL cognitive functioning and EQ-TIPS-3L suggests further research is needed on this potentially missing construct.

Indexed as

EQ-TIPShealth-related quality of lifeinfantsPedsQLtoddlers

Identifiers

PMID41268146
PMCPMC12629638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.