Evidence map›Paper›PMID 41268141›Full record

SynthesisTopics in spinal cord injury rehabilitation2025

Behavioral/Physical and Stimulation Interventions for Chronic Pain Following Spinal Cord Injury: A Systematic Review.

Linda Ehrlich-Jones, Elise Olsen, Angelika Kudla, Jennifer Burns, Nicole Sharf, Q Eileen Wafford, Allen W Heinemann

Abstract readSystematic Review
In one paragraph

Synthesis in Topics in spinal cord injury rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linda Ehrlich-JonesShirley Ryan AbilityLab, Chicago, Illinois.
Elise OlsenShirley Ryan AbilityLab, Chicago, Illinois.
Angelika KudlaShirley Ryan AbilityLab, Chicago, Illinois.
Jennifer BurnsShirley Ryan AbilityLab, Chicago, Illinois.
Nicole SharfThe Chicago School, Chicago, Illinois.
Q Eileen WaffordNorthwestern University Feinberg School of Medicine, Galter Health Sciences Library and Learning Center, Chicago, Illinois.
Allen W HeinemannShirley Ryan AbilityLab, Chicago, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Investigators have evaluated pharmacological and behavioral/physical interventions for chronic pain following spinal cord injury (SCI). A decade-old systematic review found that evidence was insufficient to conclude that nonpharmacological interventions (behavioral/physical) are effective in reducing chronic pain. Objectives: To summarize and evaluate recent peer-reviewed literature on the efficacy of nonpharmacological interventions for chronic pain. Methods: Authors searched for articles published from 2013 to August 2023 in MEDLINE, Cochrane Library, Scopus, CINAHL, and PsycINFO. Inclusion criteria were being 18 years or older, having traumatic SCI diagnosis, and having chronic pain symptoms. Interventions included nonpharmacological interventions-behavioral, complementary, and alternative medicine-and a control group. The primary outcome was pain symptom reduction. Coauthors applied these criteria and reconciled disagreements via unanimous consensus. Coauthors independently extracted data and then reviewed and revised extracted data to assure consistency and completeness. Two reviewers independently assigned a quality score using Hawker's guidelines and assigned a bias score using Cochrane risk-of-bias (RoB2) and Risk Of Bias In Non-randomized Studies (ROBINS-I) tools; they reconciled disagreements. Results: Database searches produced 2961 results; 26 proceeded to data extraction, of which 15 used behavioral/physical interventions and 11 used stimulation interventions. Discussion: Knowledge of behavioral/physical intervention methods and an evidence base with other populations are sufficient to recommend cognitive behavioral therapy and variants, particularly for neuropathic pain. In contrast, stimulation treatments are not sufficiently standardized, require equipment and expertise that is not widely disseminated, and have generated limited evidence that is not adequate to support clinical adoption with a high level of confidence. The studies highlight the importance of tailoring interventions to individuals' needs and preferences.

Indexed as

Behavior TherapyChronic PainPain ManagementPhysical Therapy ModalitiesSpinal Cord InjuriesHumanschronic painmagnetic field therapyneuropathic painnociceptive painrehabilitationspinal cord injuriessystematic reviewtreatment behavior

Identifiers

PMID41268141
PMCPMC12629207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.