Evidence map›Paper›PMID 41268127›Full record

ArticleTopics in spinal cord injury rehabilitation2025

Effects of Opioid Use Duration on Complications and Healthcare Utilization and Costs in Spinal Cord Injury.

Elsa Alvarez Madrid, David Levin, Samuel Kimmell, Maxwell Boakye, Beatrice Ugiliweneza, Camilo Castillo

Abstract read
In one paragraph

Article in Topics in spinal cord injury rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elsa Alvarez MadridKentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, Kentucky.
David LevinDepartment of Neurosurgery, School of Medicine, University of Louisville, Louisville, Kentucky.
Samuel KimmellDepartment of Neurosurgery, School of Medicine, University of Louisville, Louisville, Kentucky.
Maxwell BoakyeDepartment of Neurosurgery, School of Medicine, University of Louisville, Louisville, Kentucky.
Beatrice UgiliwenezaKentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, Kentucky.
Camilo CastilloDepartment of Neurosurgery, School of Medicine, University of Louisville, Louisville, Kentucky.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic pain management with opioids after spinal cord injury (SCI) has been shown to be ineffective, leading to overuse in length and dosage. Objectives: To assess how the length of opioid use affects associated complications and healthcare usage and costs over 12 months following injury. Methods: Adults with SCI from MarketScan Database (2000-2021) were followed up 12 months pre- and post-injury. Opioid use (OU) was screened from injury. Individuals were then classified accordingly: no use (No OU), 3 months use (OU 3m), 3 to 6 months use (OU 3-6m), and 6 to 12 months use (OU 6-12m). Related complications, healthcare utilization, and payment outcomes were compared using multivariable generalized linear regressions. Results: Cohort was composed of 9630 individuals (median age 54; 59% males). Prolonged-use group (OU 6-12m) had a different profile compared to the No OU group: younger, higher rates of males, bone fracture, thoracic injuries, and Medicaid insurance (median age 49 vs. 58; males 62% vs. 56%, fracture 58% vs. 50%, thoracic 29% vs. 21%, Medicaid 32% vs. 24%; all Conclusion: Considering risk profiles may predict prolonged opioid use and could help clinicians design care management plans to reduce complications and the associated healthcare utilization and payments.

Indexed as

Analgesics, OpioidChronic PainHealth Care CostsPatient Acceptance of Health CareSpinal Cord InjuriesAdultAgedFemaleHumansMaleMiddle AgedTime FactorsAnalgesics, Opioidhealth care costsopium dependencespinal cord injuries

Identifiers

PMID41268127
PMCPMC12629212

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.