ArticleTransplantation direct2025
Incidence and Risk Factors for Infection in Heart Transplant Recipients on Posttransplant Extracorporeal Membrane Oxygenation (ECMO).
Article in Transplantation direct, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients.Transplant infectious disease : an official journal of the Transplantation SocietyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The use of extracorporeal membrane oxygenation (ECMO) after transplantation seems to be associated with an increased risk for infectious complications. We assessed the impact of ECMO use on the incidence of infectious diseases in a nationwide cohort of heart transplant recipients. Methods: Patients undergoing heart transplantation between 2008 and 2017 and enrolled in the Swiss Transplant Cohort Study were included. We calculated incidence rates of infection at 1-y posttransplant and used Cox regression to identify infection-associated risk factors according to the pathogen group. Results: We included 306 heart transplant recipients of whom 42 patients (13.7%) received ECMO in the posttransplant period. Incidence rates at 1 y for overall infection were 259 per 100 patient-years in the ECMO group (176 for bacterial, 52 for viral and 36 for fungal infections) and 126 per 100 patient-years in the non-ECMO group (68 for bacterial, 45 for viral and 14 for fungal infections). In the ECMO group, gram-negative bacterial infections predominated over gram-positive pathogens. Use of ECMO was associated with an increased risk of overall infections (hazard ratio 1.81 [95% CI. 1.02-3.19], Conclusions: In this nationwide cohort of heart transplant recipients, the use of ECMO was associated with an increased risk for overall and fungal infections. More studies are needed to evaluate whether ECMO is independently associated with infection or a surrogate for a more critical patient condition.
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Registered trials
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