Evidence map›Paper›PMID 41268039›Full record

ArticleCureus2025

Chest Pain After Vomiting: Recognizing Boerhaave Syndrome in the Emergency Department.

Mahnoor Tayyib, Muhammad Faizan Latif, Ahmed Sakr, Amr Mahmoud

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahnoor TayyibEmergency Medicine, Lincoln County Hospital, United Lincolnshire Hospitals NHS Trust, Lincoln, GBR.
Muhammad Faizan LatifAcute Medicine, Lincoln County Hospital, United Lincolnshire Hospitals NHS Trust, Lincoln, GBR.
Ahmed SakrEmergency Department, Lincoln County Hospital, United Lincolnshire Hospitals NHS Trust, Lincoln, GBR.
Amr MahmoudEmergency Department, Lincoln County Hospital, United Lincolnshire Hospitals NHS Trust, Lincoln, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boerhaave syndrome is a rare but potentially fatal condition characterized by spontaneous transmural rupture of the esophagus, most often triggered by a sudden rise in intraluminal pressure against a closed glottis following forceful retching. Its clinical presentation can mimic other life‑threatening thoracic emergencies such as myocardial infarction, pulmonary embolism, or aortic dissection. A 50-year-old man presented to the Emergency Department with sudden onset of severe central chest pain radiating to the left side associated with shortness of breath, following multiple episodes of forceful vomiting. On examination, he was hemodynamically stable. Chest and soft-tissue neck radiographs demonstrated surgical emphysema, and a contrast-enhanced CT scan of the chest confirmed esophageal rupture with extraluminal air and food residue. The patient was managed with intravenous fluids, broad-spectrum antibiotics, and urgent cardiothoracic referral for definitive management. This case highlights the importance of maintaining a high index of suspicion for Boerhaave syndrome in patients presenting with chest pain following episodes of forceful vomiting, as early recognition and prompt intervention are vital to reduce morbidity and mortality.

Indexed as

boerhaave’s syndromechest painoesophageal rupturesurgical emphysemavomiting

Identifiers

PMID41268039
PMCPMC12628348

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.