Evidence map›Paper›PMID 41267858›Full record

ArticleFrontiers in medicine2025

Effects of the primary lung infection on outcomes in patients with severe ARDS treated with ECMO: a retrospective analysis.

Martin Mirus, Lars Heubner, Martin Brückner, Thomas Birkner, Andreas Güldner, Axel Rand, Mario Menk, Paul Leon Petrick, Hani Harb, Peter Markus Spieth

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Martin MirusDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Lars HeubnerDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Martin BrücknerDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Thomas BirknerTechnische Universität Dresden, Dresden, Germany.
Andreas GüldnerDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Axel RandDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Mario MenkDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Paul Leon PetrickDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Hani HarbTechnische Universität Dresden, Dresden, Germany.
Peter Markus SpiethDepartment of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (vvECMO) remains associated with high mortality. Whether etiology-based differentiation within infectious ARDS improves prognostic and therapeutic precision remains unclear. This study compared vvECMO-treated ARDS patients with different pulmonary infections to identify clinically relevant etiology-specific differences. Methods: The retrospective single-center cohort study included adult patients who received vvECMO for severe infectious pulmonary ARDS between 2014 and 2021. Patients were categorized into Covid-19 ( Results: Non-Covid ARDS patients had greater disease severity at ECMO initiation, although mortality was lower: SOFA score (15.7 vs. 13.7; Conclusion: Even within primary infectious pulmonary ARDS, substantial heterogeneity exists. The underlying infection critically affects the prognostic value of clinical parameters, organ dysfunctions, and scoring systems in vvECMO-treated patients. Considering ARDS etiology may improve risk stratification and guide individualized therapy. Trial registration: German Clinical Trials Register (DRKS00027856), https://drks.de/search/en/trial/DRKS00027856.

Indexed as

ARDScritical careECMOinfectionsphenotypingsepsis

Identifiers

PMID41267858
PMCPMC12626973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.