Evidence map›Paper›PMID 41267840›Full record

ArticleEuropean heart journal. Digital health2025

Echocardiographic measures read by artificial intelligence enable accurate and rapid prediction of the worsening of heart failure.

Tony Hauptmann, Sven-Oliver Tröbs, Andreas Schulz, Aida Romano Martinez, Philipp Lurz, Jürgen Prochaska, Philipp Sebastian Wild, Stefan Kramer

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal. Digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04064450 (MyoVasc - An Epidemiological Cohort Study to Investigate the Development and Progression of Heart Failure and the Interaction With Vascular Disease), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04064450 active not recruitingnot on this map

MyoVasc - An Epidemiological Cohort Study to Investigate the Development and Progression of Heart Failure and the Interaction With Vascular Disease

TypeobservationalSponsorJohannes Gutenberg University MainzRan2013 to 2028Enrolled3,289ConditionsHeart Failure
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Diagnostic Tests for Stage B Heart Failure.Current cardiology reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tony HauptmannInstitute of Computer Science, Johannes Gutenberg University Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0003-1964-6568
Sven-Oliver TröbsPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Andreas SchulzPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Aida Romano MartinezPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Philipp LurzDZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, Mainz, Germany.
Jürgen ProchaskaPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Philipp Sebastian WildPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Stefan KramerInstitute of Computer Science, Johannes Gutenberg University Mainz, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Automatic echocardiographic measurements using artificial intelligence have shown promising results; however, they have not been compared with manual measurements regarding heart failure (HF) progression and algorithm runtime. Methods and results: Data came from the prospective HF study MyoVasc (NCT04064450), which involved a highly standardized 5-h examination, including comprehensive echocardiography, at a dedicated study centre between January 2013 and April 2018. Worsening of HF was a primary composite endpoint, recorded by structured follow-up, death certificates, and medical records. The automated assessment was performed using EchoDL, eight 3D convolutional neural networks (CNNs) trained to predict clinical parameters. Manual and automatic left ventricular ejection fraction (LVEF), Conclusion: Automated analysis of echocardiograms using 3D CNNs was comparable to manual measurements in predicting HF-specific outcomes. Echo-DL offers potential time savings and improved risk prediction in clinical settings, allowing integration into echocardiographic hardware.

Indexed as

Artificial intelligenceEchocardiographyMachine learningWorsening of heart failure

Identifiers

PMID41267840
PMCPMC12629647

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.