Evidence map›Paper›PMID 41267681›Full record

ArticleNAR molecular medicine2025

Investigation of the PIWI-interacting RNA expression differences in normoresponder and diminished ovarian reserve follicular fluid.

Çağrı Öner, Zafer İşdar, Nergis Özlem Kiliç, Duygu Kütük, Belgin Selam, Ertuğrul Çolak

Abstract read
In one paragraph

Article in NAR molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Çağrı ÖnerKırklareli University, Medical Faculty, Department of Medical Biology, 39010, Kırklareli, Turkey.
Zafer İşdarMaltepe University, School of Medicine, 34857, İstanbul, Turkey.
Nergis Özlem KiliçMaltepe University, School of Medicine, Department of Histology and Embryology, 34857, İstanbul, Turkey.
Duygu KütükMaltepe University, School of Medicine, Department of Histology and Embryology, 34857, İstanbul, Turkey.
Belgin SelamAcibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Obstetrics and Gynecology, 34752, İstanbul, Turkey.
Ertuğrul ÇolakEskişehir Osmangazi University, Medical Faculty, Department of Biostatistics, 26040, Eskişehir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PIWI-interacting RNAs (piRNAs) and the subgroup of argonaute (AGO) proteins that collaborate with PIWI proteins are essential for cell repair, heterochromatin modifications, and PIWI-dependent transposon silencing. The genome stability of somatic and germ cells is maintained by small noncoding RNAs called piRNAs, which are also essential for transposon silencing. It is thought that during gametogenesis, PIWI proteins and piRNAs protect the gamete's genome stability. In the present study, isolated cumulus cells from follicular fluid (FF) were used to assess the expression of the PIWIL3 gene and the piR-651, piR-823, and piR-16993 between normoresponder (NOR) and diminished ovarian reserve (DOR) cases. According to the data, no statistically significant result was observed in piR-651 expression in DOR. Conversely, the DOR group's expression of piR-823 and piR-16993 decreased compared to the NOR (

Identifiers

PMID41267681
PMCPMC12628311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.