Evidence map›Paper›PMID 41267658›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

Global distribution of Xpert CT/NG assay

Daniel Golparian, Maria Luiza Bazzo, Pamela Cristina Gaspar, Magnus Unemo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel GolparianWHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Maria Luiza BazzoMolecular Biology, Microbiology and Serology Laboratory, Federal University of Santa Catarina, Florianópolis, Brazil.
Pamela Cristina GasparDepartment of HIV/AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infection, Secretariat of Health Surveillance and Environment, Ministry of Health of Brazil, Brasília, Brazil.
Magnus UnemoWHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening of 54,837 gonococcal genomes identified 12 new variants lacking one (n = 9) or both (n = 3) of the Xpert CT/NG assay's gonococcal targets. In total, 17 diagnostic-escape variants occurred across five countries and multiple genomic lineages; phylogenomic analysis revealed both ancestral and strain-specific recombination events. Xpert CT/NG diagnostic escape remains rare (0.026%) but illustrates recurrent recombination in gonococci. This emphasises the necessity of continuous external quality assessments, supplementary testing of gonococcal-positive molecular screening samples, and appropriate genomic and epidemiologic surveillance.

Indexed as

GonorrheaMolecular Diagnostic TechniquesNeisseria gonorrhoeaeGenetic VariationGenome, BacterialHumansPhylogenyantimicrobial resistancediagnostic-escape variantGeneXpertgonorrhoeamultidrug-resistant N. gonorrhoeae (MDR-GC)Neisseria gonorrhoeaetravelXpert CT/NG

Identifiers

PMID41267658
PMCPMC12639276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.