Evidence map›Paper›PMID 41267609›Full record

ReviewThe clinical respiratory journal2025

Follicular Dendritic Cell Sarcoma in Mediastinum: A Case Study and Literature Review.

Qingxia Xu, Chong Zhang, Yang Ma, Longquan Xiang

Abstract readCase ReportsReview
In one paragraph

Review in The clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qingxia XuDepartment of Pathology, Jining No. 1 People's Hospital, Jining, Shandong, China.
Chong ZhangDepartment of Pathology, Jining No. 1 People's Hospital, Jining, Shandong, China.
Yang MaDepartment of Respiratory Medicine, Decheng District Hospital of Traditional Chinese Medicine, Dezhou, China.
Longquan XiangDepartment of Pathology, Jining No. 1 People's Hospital, Jining, Shandong, China.ORCID https://orcid.org/0009-0004-5738-5906

Funding

Key R&D Program of Jining 2023YXNS222Natural Science Foundation of Shandong Province ZR2014HP014
6 · The paper itself

Abstract

Follicular dendritic cell sarcoma (FDCS) is an uncommon malignant neoplasm that arises from follicular dendritic cells (FDCs). The mediastinum is a more unusual site of FDCS. In this document, we detail a case involving the complete surgical removal of FDCS located in the mediastinum. A 28-year-old woman presented with symptoms of right chest pain. Accompanying symptoms include chest tightness, shortness of breath, and faintness. Chest computed tomography was performed and revealed abnormal enhancement in the mediastinal region. An excisional biopsy was carried out, and through the aid of immunohistochemistry (IHC), a diagnosis of FDCS was confirmed. Following surgery, the patient underwent radiotherapy for 27 sessions. The patient was followed up by the oncology service for 6 years and was still alive at the time of drafting this report. This exceedingly uncommon case underscores the challenges in making a differential diagnosis and emphasizes the significance of diagnostic indicators, including histopathology and IHC, in establishing a diagnosis. Clinicians should be alert to the possibility of encountering this disease and take into consideration various characteristics to avoid misdiagnosis.

Indexed as

Dendritic Cell Sarcoma, FollicularMediastinal NeoplasmsMediastinumAdultBiopsyDiagnosis, DifferentialFemaleHumansImmunohistochemistryTomography, X-Ray Computeddiagnosisfollicular dendritic cell sarcomaimmunohistochemistrymediastinum

Identifiers

PMID41267609
PMCPMC12635493

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.