Evidence map›Paper›PMID 41267533›Full record

Observational studyJournal of gynecologic oncology2026

Exploring willingness to pay out-of-pocket for genetic testing among ovarian cancer patients in Malaysia, a middle-income country in Asia.

Heamanthaa Padmanabhan, Ka Keat Lim, Nur Tiara Hassan, Nor Syuhada Ahmad Bashah, Yong-Quan Lee, Joanna Lim, Ik Hui Teo, Yogeeta Gunasagran, Rubandra Kumaar Kalimuthu, Jamil Omar and 14 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of gynecologic oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. BRCA Testing in Asian Patients with Ovarian Cancer: Standard Clinical Practice or Mutation Prediction Model?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Heamanthaa PadmanabhanGenetic Counselling Unit, Cancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0009-0003-6576-6031
Ka Keat LimDepartment of Population Health Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-2340-4097
Nur Tiara HassanGenetic Counselling Unit, Cancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0000-0001-8282-0034
Nor Syuhada Ahmad BashahGenetic Counselling Unit, Cancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0009-0002-7376-9008
Yong-Quan LeeGenetic Counselling Unit, Cancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-2714-3821
Joanna LimCore Laboratory Unit, Cancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-0075-3486
Ik Hui TeoDepartment of Gynaeoncology, University Malaya Medical Centre, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0003-2643-5259
Yogeeta GunasagranDepartment of Gynaeoncology, University Malaya Medical Centre, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0009-0003-7618-5603
Rubandra Kumaar KalimuthuDepartment of Gynaeoncology, University Malaya Medical Centre, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0009-0007-6230-3890
Jamil OmarDepartment of Gynaeoncology, National Cancer Institute, Putrajaya, Malaysia.ORCID https://orcid.org/0000-0002-3390-1978
Mohd Norazam Mohd AbasDepartment of Gynaeoncology, National Cancer Institute, Putrajaya, Malaysia.ORCID https://orcid.org/0000-0002-4207-9058
Vickneswaren Thever RamasamyDepartment of Gynaeoncology, Hospital Ampang, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-2400-3145
Chee Meng YongDepartment of Gynaeoncology, Hospital Ampang, Selangor, Malaysia.ORCID https://orcid.org/0000-0001-8214-7417
Mohamad Faiz Mohamed JamliDepartment of Gynaeoncology, Hospital Tuanku Jaafar Seremban, Seremban, Malaysia.ORCID https://orcid.org/0009-0001-7156-516X
Wee Wee SimDepartment of Gynaeoncology, Hospital Umum Sarawak, Kuching, Malaysia.ORCID https://orcid.org/0000-0002-8530-5094
Ahmad Muzamir Ahmad MustafaDepartment of Gynaeoncology, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia.ORCID https://orcid.org/0009-0001-6897-1562
Nor Huda Mat AliDepartment of Gynaeoncology, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia.ORCID https://orcid.org/0009-0009-8374-4905
Ismail AliyasDepartment of Gynaecology, Hospital Sultanah Bahiyah, Alor Setar, Malaysia.ORCID https://orcid.org/0009-0007-4002-6247
Keng Joo LimDepartment of Gynaecology, KPJ Johor Specialist Hospital, Johor Bahru, Malaysia.ORCID https://orcid.org/0009-0006-5342-4554
Meow Keong ThongGenetics and Metabolism Unit, Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-7288-7910
Yin Ling WooDepartment of Gynaeoncology, University Malaya Medical Centre, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0003-1742-1066
Asrul Akmal ShafieSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.ORCID https://orcid.org/0000-0002-5629-9270
Soo-Hwang TeoCancer Research Malaysia, Selangor, Malaysia.ORCID https://orcid.org/0000-0002-0444-590X
Sook-Yee YoonGenetic Counselling Unit, Cancer Research Malaysia, Selangor, Malaysia. sookyee.yoon@cancerresearch.my.ORCID https://orcid.org/0000-0002-9992-0901

Funding

Yayasan PETRONASYayasan Sime Darby
6 · The paper itself

Abstract

objectiveOur previous study demonstrated that training oncologists to provide genetic counselling for ovarian cancer patients in Malaysia, an upper-middle-income Asian country, increased uptake of genetic testing to 80% when the test was free under research. However, in practice, genetic tests are unlikely to be provided for free in low-and-middle-income countries. In this study, we explored the willingness to pay (WTP) for genetic testing among ovarian cancer patients in Malaysia.

methodsIn this multi-center study, ovarian patients without prior genetic counselling were administered questionnaires on WTP (a contingent valuation exercise), facilitators and barriers to genetic counselling, and followed up for at least 6 months. We estimated the WTP value and explored factors associated with being willing to pay using logistic regression.

resultsOf 100 sequential patients recruited, 58% stated WTP for genetic testing at median of MYR1,000 (interquartile range=MYR1,125). Older participants were less likely to be willing to pay (odds ratio=0.95; 95% confidence interval=0.91-0.99). Reasons for being unwilling to pay included affordability (71%), belief that it should be paid by government or insurance (19%) and preference not to know their genetic status (14%). At the end of follow-up (mean 5±17 months), 17% took the test at full price.

conclusionIn this exploratory study, stated WTP for genetic testing was high but only at a reduced price. At follow-up, only a minority of patients paid the full price. A co-payment framework or subsidy scheme may be needed to reduce the significant cost barriers to genetic testing in Malaysia.

Indexed as

Financing, PersonalGenetic TestingHealth ExpendituresOvarian NeoplasmsAdultAgedFemaleGenetic CounselingHumansMalaysiaMiddle AgedSurveys and QuestionnairesAsiaGenetic TestingOvarian CancerSubsidy

Identifiers

PMID41267533
PMCPMC13226085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.