Evidence map›Paper›PMID 41267171›Full record

ArticleAnalytical chemistry2025

Cryogenic Gas-Phase Infrared Ion Spectroscopy of Ultraviolet-Induced Nucleotide Photoproducts.

Gurpur Rakesh D Prabhu, Michael Götze, Kim Greis, América Y Torres-Boy, Marc Safferthal, Dominika Strzelecka, Carla Kirschbaum, Nimish D Deshpande, Niklas Geue, Gerard Meijer and 2 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gurpur Rakesh D PrabhuDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0000-0002-3237-212X
Michael GötzeDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.
Kim GreisDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0000-0002-9107-2282
América Y Torres-BoyDepartment of Molecular Physics, Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, Berlin 14195, Germany.
Marc SafferthalDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0009-0006-9267-3940
Dominika StrzeleckaDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.
Carla KirschbaumDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0000-0003-3192-0785
Nimish D DeshpandeDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.
Niklas GeueDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0000-0002-5216-8353
Gerard MeijerDepartment of Molecular Physics, Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, Berlin 14195, Germany.ORCID 0000-0001-9669-8340
Gert von HeldenDepartment of Molecular Physics, Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, Berlin 14195, Germany.ORCID 0000-0001-7611-8740
Kevin PagelDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Altensteinstraße 23a, Berlin 14195, Germany.ORCID 0000-0001-8054-4718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultraviolet (UV) exposure induces cross-linked pyrimidine dimers in nucleic acids, primarily forming cyclobutane pyrimidine dimers and 6-4 pyrimidine-pyrimidone adducts. These photoproducts exist in multiple isomeric forms, and various dimeric combinations involving thymine, cytosine, and uracil have been documented since the 1960s. Mass spectrometry (MS) has been pivotal in identifying these species, although condensed-phase spectroscopy remains essential for full structural elucidation. This study integrates MS with gas-phase infrared (IR) spectroscopy to obtain vibrational spectra (800-1900 cm

Indexed as

NucleotidesPyrimidine DimersUltraviolet RaysDensity Functional TheoryGasesSpectrophotometry, InfraredTandem Mass SpectrometryGasesNucleotidesPyrimidine Dimers

Identifiers

PMID41267171
PMCPMC12874228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.