Evidence map›Paper›PMID 41267132›Full record

SynthesisSystematic reviews2025

Coping with copper: a bibliometric analysis of copper's role in cancer pathogenesis and treatment.

Chaofan Chen, Qi Su, Min Zi, Yunchun Duan, Zhiyun Zhang

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaofan ChenDepartment of Anorectal, Kunming Municipal Hospital of Traditional Chinese Medicine, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, No. 25 Dongfeng East Road, Panlong District, Kunming, Yunnan, 650011, China.
Qi SuDepartment of Neonatology, Baoshan People's Hospital, Baoshan, China.
Min ZiDepartment of General Surgery, Baoshan People's Hospital, Baoshan, China.
Yunchun DuanTraditional Chinese Medicine Department, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zhiyun ZhangDepartment of Anorectal, Kunming Municipal Hospital of Traditional Chinese Medicine, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, No. 25 Dongfeng East Road, Panlong District, Kunming, Yunnan, 650011, China. jianchidaodi_2010@163.com.ORCID 0009-0000-0856-7392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This bibliometric analysis on copper's role in cancer pathogenesis and treatment, spanning from 2014 to 2024, provides a comprehensive overview of current trends and emerging research areas. It highlights China's dominance in research output and identifies a seminal 2022 study by Tsvetkov Peter as the most cited, cementing its importance in the field. Central keywords such as "DNA damage," "trace elements," and "oxidative stress" reflect the critical roles copper plays in cancer biology. As the field continues to evolve, key areas of focus for future studies are expected to include copper homeostasis, the roles of cuproptosis and ferroptosis, and the development of cancer prognosis models based on cuproptosis. This analysis offers valuable insights for advancing both scientific inquiry and clinical applications in this area.

Indexed as

BibliometricsCopperNeoplasmsDNA DamageHumansOxidative StressCopperCiteSpaceCopper homeostasisCuproptosisVisualization analysisVOSviewer

Identifiers

PMID41267132
PMCPMC12636198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.