ReviewOne health outlook2025
Integrating neurological expertise into One Health strategies for pediatric neurocysticercosis-associated epilepsy control in Sub-Saharan Africa: a narrative review.
Review in One health outlook, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeurocysticercosis (NCC), caused by the larval stage of Taenia solium, is a leading preventable cause of epilepsy in children, particularly in Sub-Saharan Africa (SSA), where inadequate sanitation practices and limited veterinary control strategies persist. A missing link in the One Health response to NCC has been the absence of communication between neurospecialists and the other partners in control strategies. This narrative review explores how integrating neurological expertise into One Health strategies can enhance the prevention and control of NCC-associated epilepsy in children across the region.
methodsWe reviewed literature from PubMed/MEDLINE, Scopus, Google Scholar, Embase, Web of Science, Global Health, CINAHL, PsycINFO, and the African Index Medicus, including peer-reviewed articles and organizational reports published between 2013 and March 2025. FINDINGS AND
conclusionOut of 1,509 records screened, 28 studies met the inclusion criteria, focusing on neuroparasitosis-associated epilepsy in children across SSA. These included research on disease burden and care challenges (n = 10), pathogenesis (n = 8), One Health control strategies (n = 4), and implementation barriers and solutions (n = 6). NCC remains a major contributor to pediatric epilepsy and associated disability in SSA. A One Health approach informed by direct input from neuro-specialists and better recording of infectious causes of epilepsy can assist teams to implement key strategies, including community education, improved sanitation, food safety measures, pig vaccination, and mass drug administration. Strengthening intersectoral collaboration and healthcare access is critical to reducing NCC burden and improving neurological outcomes for affected children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.