Evidence map›Paper›PMID 41267038›Full record

ArticleBMC nephrology2025

Insights on the practical application of the current treatment consensus in rhabdomyolysis management: a case report.

Theresa Gier, Sebastian Koball, Matteo Marcello, Faeq Husain-Syed, Gonzalo Ramírez-Guerrero, Thiago Reis, Steffen Mitzner, Jens-Christian Schewe, Daniel Reuter, Claudio Ronco and 1 more

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Theresa GierDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Center Rostock, Rostock, Germany.
Sebastian KoballDepartment of Nephrology, University Medical Center Rostock, Rostock, Germany.
Matteo MarcelloInternational Renal Research Institute of Vicenza (IRRIV), Vicenza, Italy.
Faeq Husain-SyedPulmonology and Critical Care Medicine, Member of the German Centre for Lung Research, University Hospital Giessen and Marburg, Giessen, Germany.
Gonzalo Ramírez-GuerreroInternational Renal Research Institute of Vicenza (IRRIV), Vicenza, Italy.
Thiago ReisInternational Renal Research Institute of Vicenza (IRRIV), Vicenza, Italy.
Steffen MitznerDepartment of Nephrology, Dialysis and Kidney Transplantation, San Bortolo Hospital, Vicenza, Italy.
Jens-Christian ScheweDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Center Rostock, Rostock, Germany.
Daniel ReuterDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Center Rostock, Rostock, Germany.
Claudio RoncoInternational Renal Research Institute of Vicenza (IRRIV), Vicenza, Italy.
Gerd KlinkmannDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Center Rostock, Rostock, Germany. gerd.klinkmann@uni-rostock.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemoadsorption has emerged as a promising adjunctive therapy in the management of various inflammatory and toxin-mediated conditions. Its role in context of rhabdomyolysis has generated increasing scientific and clinical interest. In response to the recent consensus statement by an international expert task force—published in BMC Nephrology in July 2024—regarding the use of hemoadsorption in rhabdomyolysis, we aim to contribute further to this evolving discourse. CASE PRESENTATION: We report on a patient with severe rhabdomyolysis secondary to influenza B infection who suffered acute kidney injury (AKI) as a result. Alongside conservative treatment, we successfully implemented a combined regimen of CRRT and hemoadsorption, while using myoglobin levels up- and downstream of the adsorber as a tool for therapy monitoring. The patient subsequently recovered complete renal function and full body mobility.

conclusionThe case illustrates the practical implementation of hemoadsorption within a multimodal treatment strategy. In addition to demonstrating concordance with current consensus guidelines, we seek to critically discuss potential refinements in the therapeutic approach—particularly concerning monitoring strategies and the integration of extracorporeal modalities—to facilitate future clinical practice and research.

Indexed as

Acute Kidney InjuryRhabdomyolysisAdolescentCombined Modality TherapyConsensusHumansMaleMyoglobinMyoglobinCase reportCRRTHemoadsorptionRhabdomyolysis

Identifiers

PMID41267038
PMCPMC12631998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.