Observational studyBMC pulmonary medicine2025
Remote monitoring of spirometry and oximetry in patients with connective tissue disease related interstitial lung disease: a prospective observational cohort study.
Observational study in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06702228 (Precision Diagnosis and Care for Families With Pulmonary Fibrosis in Ireland [PRECISE-PF]), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Precision Diagnosis and Care for Families With Pulmonary Fibrosis in Ireland [PRECISE-PF]
Who cites it
1 citing paper in PubMed.
- Beyond scarring: a next-generation vision for pulmonary fibrosis management.Molecular biology reports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundRemote monitoring of forced vital capacity (FVC) and oximetry (SpO2) in patients with idiopathic pulmonary fibrosis (IPF) is emerging as an adjunct to routine in-person ambulatory care. Patients with connective tissue diseases (CTD) commonly have impaired hand function, diminished oral aperture and Raynaud's phenomenon, which can uniquely impair the user’s ability to use these devices. We aimed to assess the acceptability, usability and adherence to home monitoring in patients with CTD associated interstitial lung disease (CTD-ILD) compared to patients with IPF.
methodsParticipants were recruited to a prospective observational cohort study (NCT06702228), provided with a portable handheld spirometer and finger pulse oximeter connected to a smart phone application (app), received training in their use, asked to use these at least once a week, and were reviewed at 6-months.
resultsNinety-seven participants completed the 6-month study. Participants in the CTD-ILD group were slightly younger than those with IPF with a mean and standard deviation (SD) of 62.44 (15.25) compared to 70.21 (9.39) years (p = 0.005). The number of days the devices were used was lower in the CTD-ILD (69.2 versus 99.4, p = 0.028). In line with study instructions, there was no significant difference in weekly adherence with FVC or SpO2 measurement (71.5% versus 75%, p = 0.65). We found a strong correlation between home and hospital-based FVC (r = 0.76, p < 0.0001). Both groups reported finding the devices and app easy to use (77% versus 72%, p = 0.65), but more participants with CTD-ILD reported difficulty obtaining SpO2 readings compared to those with IPF (33.33% versus 12.77%, p = 0.02). Six (16.7%) participants from the CTD-ILD group experienced difficulty using the devices due to hand function impairment (p = 0.004), 3 (8.3%) were unable to use a finger probe at all and required an ear oximeter. We found no differences in the correlation of FVC adherence with age, ILD-GAP score, or participant reported symptom scores between the groups.
conclusionsWhile participants with CTD-ILD had lower device use than those with IPF, they did have high adherence, satisfaction and reported ease of use despite Raynaud's phenomenon and impaired hand function. Therefore, remote monitoring has potential as an adjunct to routine care in CTD-ILD.
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