Evidence map›Paper›PMID 41266985›Full record

ArticleBMC plant biology2025

Insights into double sigmoid pattern during Chinese cherry fruit development through comparative physiological and transcriptomic profiles.

Yan Wang, Yan Ma, Fengting Huang, Yunfan Yang, Hanmei Du, Wen He, Yuanxiu Lin, Yunting Zhang, Mengyao Li, Yong Zhang and 5 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yan WangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yan MaCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Fengting HuangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yunfan YangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Hanmei DuPanxi Featured Crops Research and Utilization Key Laboratory of Sichuan Province, Xichang University, Xichang, Sichuan, 615000, China.
Wen HeCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yuanxiu LinCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yunting ZhangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Mengyao LiCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yong ZhangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Ya LuoCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Zhiwei WuCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Haoru TangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Qing ChenCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China. supnovel@sicau.edu.cn.
Xiaorong WangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China. wangxr@sicau.edu.cn.

Funding

Sichuan Fruit Innovation Team of National Modern Agricultural Industrial Technology System in China SCCXTD-2024-4Sichuan Science and Technology Program 2024YFHZ0302
6 · The paper itself

Abstract

backgroundChinese cherry [Cerasus pseudocerasus (Lindl.) G.Don] (syn. Prunus pseudocerasus Lindl), native to China, is an important fruiting cherry species belonging to the Rosaceae family. Fruit size is a key factor limiting the large-scale production of this crop. However, the regulatory mechanisms governing fruit size in Chinese cherry remain poorly understood.

resultsIn this study, we analyzed comparative physiological characteristics and performed transcriptome sequencing to identify key genes regulating fruit size in Chinese cherry. The increase in fruit diameter and weight follows a typical double-sigmoid growth pattern. The final fruit size is attributed to both cell division and cell expansion, corresponding to Sigmoid I (SI) and Sigmoid II (SII), respectively. Auxin, gibberellin, cytokinin, and brassinosteroids showed a marked increase during the SI phase, followed by varying degrees of decrease during the slow-growth stage, and a slight increase during the SII phase. During SI phase, IAA, GA3, and ZR exhibited much higher levels or more rapid increases in large fruits (HF) compared to small fruits (PJHH), indicating their important roles in early fruit enlargement. Comparative transcriptomic analysis identified a total of 8,938 DEGs through pairwise comparisons across SI and SII phases between HF and PJHH. Gene Ontology (GO) enrichment analysis revealed that numerous genes associated with cell cycle and phytohormones, including auxin, gibberellin, and cytokinin, exhibited differential expression between large- and small-fruited landraces. Some candidate genes were validated by RT-qPCR analysis, including CpCDKB2;2, CpPAT14, CpRBR, CpGH3.1, CpARF6, CpIAA6like, CpYUCCA10, CpGA2oxlike, and CpARR5like, among others.

conclusionsThese findings provide a theoretical foundation for the regulation of fruit size in Chinese cherry breeding. In the future, new Chinese cherry cultivars with larger fruits may be bred by overexpression genes that positively regulate fruit size or by knocking out genes that negatively regulate fruit size via transgenic or gene editing technologies.

Indexed as

FruitPrunusTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantPlant Growth RegulatorsPlant Growth RegulatorsCell cycleChinese cherryDouble sigmoid patternFruit sizePlant hormone

Identifiers

PMID41266985
PMCPMC12632085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.