Evidence map›Paper›PMID 41266852›Full record

ReviewNature reviews. Chemistry2025

Integrative catalytic pairs driving complex chemical reactions.

Jie Ding, Lingyue Liu, Hong Bin Yang, Tianyu Zhang, Bin Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie Ding *Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, China.ORCID http://orcid.org/0000-0002-1427-9618
Lingyue Liu *Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID http://orcid.org/0000-0002-5000-1605
Hong Bin YangSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, China. yanghb@mail.usts.edu.cn.
Tianyu ZhangCollege of Environmental Science and Engineering, Beijing Forestry University, Beijing, China. tzhang@bjfu.edu.cn.
Bin LiuDepartment of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, China. bliu48@cityu.edu.hk.ORCID http://orcid.org/0000-0002-4685-2052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-atom catalysts are isolated metal atoms on supports that offer well-defined active sites, nearly 100% atom utilization, and exceptional activity and selectivity, making them powerful platforms in heterogeneous catalysis. However, their uniform active sites often limit performances in complex chemical reactions involving multiple intermediates. To address this, integrative catalytic pairs (ICPs) are proposed, featuring spatially adjacent, electronically coupled dual active sites that function cooperatively yet independently. Unlike single-atom catalysts or dual-atom catalysts, ICPs offer functional differentiation within a small catalytic ensemble, enabling concerted multi-intermediate reactions. This Review traces the evolution from nanocatalysts to single-cluster catalysts and single-atom catalysts, evaluating their structural challenges and mechanistic limitations. Building on this, we define ICPs, illustrate their geometric and electronic features, and classify them by atomic composition and catalytic function. We highlight nitrate reduction, CO

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.