Evidence map›Paper›PMID 41266687›Full record

ArticleNature medicine2025

Editorial Expression of Concern: Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.

Christine M Lovly, Nerina T McDonald, Heidi Chen, Sandra Ortiz-Cuaran, Lukas C Heukamp, Yingjun Yan, Alexandra Florin, Luka Ozretić, Diana Lim, Lu Wang and 29 more

Abstract readExpression of Concern
PubMed Publisher
In one paragraph

Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

39 authors.

Christine M LovlyDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA. christine.lovly@vanderbilt.edu.
Nerina T McDonaldDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Heidi ChenDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA.
Sandra Ortiz-CuaranDepartment of Translational Genomics, Center of Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Lukas C HeukampDepartment of Pathology, Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Yingjun YanDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Alexandra FlorinDepartment of Pathology, Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Luka OzretićDepartment of Pathology, Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Diana LimDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Lu WangDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Zhao ChenDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Xi ChenDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA.
Pengcheng LuDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA.
Paul K PaikDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ronglai ShenDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Hailing JinDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Reinhard BuettnerDepartment of Pathology, Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Sascha AnsénDepartment of Internal Medicine (Department I), Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Sven PernerDepartment of Prostate Cancer Research, Institute of Pathology, Center of Integrated Oncology Köln-Bonn, University Hospital of Bonn, Bonn, Germany.
Michael BrockmannDepartment of Pathology, Hospital Merheim, Cologne, Germany.
Marc BosDepartment of Translational Genomics, Center of Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Jürgen WolfDepartment of Internal Medicine (Department I), Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Masyar GardiziDepartment of Internal Medicine (Department I), Center for Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Gavin M WrightDepartment of Surgery, University of Melbourne, St. Vincent's Hospital, Melbourne, Victoria, Australia.
Benjamin SolomonDivision of Hematology and Medical Oncology, Peter MacCallum Cancer Center, Melbourne, Australia.
Prudence A RussellDepartment of Anatomical Pathology, St. Vincent's Hospital, Melbourne, Victoria, Australia.
Toni-Maree RogersDepartment of Pathology, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.
Yoshiyuki SueharaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Monica Red-BrewerDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Rudy TieuAnti-tumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Elisa de StanchinaAnti-tumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Qingguo WangDepartment of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA.
Zhongming ZhaoDepartment of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA.
David H JohnsonDepartment of Medicine, UT Southwestern School of Medicine, Dallas, Texas, USA.
Leora HornDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Kwok-Kin WongDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Roman K ThomasDepartment of Translational Genomics, Center of Integrated Oncology Köln-Bonn, University Hospital Cologne, Cologne, Germany.
Marc LadanyiDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
William PaoDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41266687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.