Evidence map›Paper›PMID 41266598›Full record

ArticleCommunications psychology2025

Early life environment moderates association of body composition and internalizing problems in adolescence.

Claudia Buss, Alice M Graham, Lauren E Gyllenhammer, Pathik D Wadhwa, Jerod M Rasmussen

Abstract read
In one paragraph

Article in Communications psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia BussDevelopment, Health and Disease Research Program, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0002-8738-3133
Alice M GrahamDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA.
Lauren E GyllenhammerDevelopment, Health and Disease Research Program, University of California, Irvine, CA, USA.
Pathik D WadhwaDevelopment, Health and Disease Research Program, University of California, Irvine, CA, USA.
Jerod M RasmussenDevelopment, Health and Disease Research Program, University of California, Irvine, CA, USA. rasmussj@hs.uci.edu.ORCID http://orcid.org/0000-0002-9400-7750

Funding

Stress and Human Stem/Progenitor Cells: Biobehavioral MechanismsR01HD107176 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kristen Elizabeth Boyle, Sonja Entringer · 2022 to 2026
$3.3M
Developmental Programming of the Human Hypothalamus and its Role in Motivated BehaviorsR01MH138481 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI Jerod Michael Rasmussen · 2025 to 2026
$785k
Synergistic effect of maternal insulin-resistance and cortisol in pregnancy on fetal programming of child mitochondrial function and obesity riskR00HD097302 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI GYLLENHAMMER, LAUREN ELIZABETH · 2022 to 2024
$744k
Fetal Programming of Human Newborn Energy Homeostasis Brain NetworksR00HD100593 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI RASMUSSEN, JEROD MICHAEL · 2023 to 2025
$744k
NICHD NIH HHS R00 HD097302NICHD NIH HHS R00 HD100593NICHD NIH HHS R01 HD107176NIMH NIH HHS R01 MH138481U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R00 HD-097302U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R00 HD-100593U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R01 HD-107176U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R01 MH-138481
6 · The paper itself

Abstract

Metabolic and depressive disorders are major chronic global health concerns, often co-occurring and mutually reinforcing each other. Thus, understanding risk and protective factors underlying their development is crucial for identifying effective preventive strategies. Participants included N = 10,446 participants (31,418 observations) from the Adolescent Brain Cognitive Development Study aged 10-15 years. Primary outcomes were internalizing problem scores, and random slopes quantifying the within-person coupling between waist-to-height ratio and internalizing problems. Predictors included early-life adversity measures and potentially protective environments measured at the family, community, peer, and school level. Early-life adversity and protective environment scores were examined as moderators of the coupling between body composition and internalizing problems. Early-life adversity was significantly associated with the magnitude of within-person coupling (random slope); individuals with higher early-life adversity exhibited a stronger coupling between waist-to-height ratio and internalizing problems (r²=4.6%, t = 26.6, p < 10

Identifiers

PMID41266598
PMCPMC12634448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.