Evidence map›Paper›PMID 41266597›Full record

ArticleBJC reports2025

'Is it my last Christmas?' Using real-world data as a prompt to reflect on goal-concordant advanced lung cancer care-a retrospective, longitudinal study.

Clara Forrest, Julie Twomey, Mansoor Qayoumi, Alex Bryan, Dearbhaile C Collins, Sinead Noonan, Karie Dennehy, Siobhán Gaynor, Pauline O'Dea, Hazel O'Sullivan and 1 more

Abstract read
In one paragraph

Article in BJC reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clara ForrestDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland. claraforrest1@hotmail.com.
Julie TwomeyDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Mansoor QayoumiDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Alex BryanDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Dearbhaile C CollinsDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Sinead NoonanDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Karie DennehyDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Siobhán GaynorCancer Trials Ireland, Dublin 2, Ireland.
Pauline O'DeaDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Hazel O'SullivanDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Seamus O'ReillyDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAdvanced non-small cell lung cancer (NSCLC) treatment paradigms include prolonged systemic anti-cancer therapy (SACT) courses. Treatment breaks during significant life events may align with patients' care goals but are poorly studied. We evaluated the temporal patterns of palliative SACT received by NSCLC patients during Christmas 2006-2023, a period during which treatment options increased.

methodsA retrospective, longitudinal study using electronic records examined palliative SACT for NSCLC in the month of December 2006-2023. It was conducted in a hospital designated as a European Society of Medical Oncology Designated Centre of Integrated Oncology and Palliative Care Services.

resultsIn December 2006-2023, 250 patients with NSCLC received palliative SACT with a mean age of 65.5 years (range: 36-94). Adenocarcinoma constituted 171 cases, and 188 patients were stage IV. During their last Christmas, 53% received palliative SACT (n = 133/250), 4% died within 30 days of treatment (n = 5/133) and 5% spent their last Christmas Eve/Day and/or Boxing Day admitted in hospital (n = 7/133). The proportion of those alive the following Christmas increased over the study period (p < 0.001).

conclusionsMost advanced NSCLC patients received palliative SACT during their last Christmas, reflecting the need for greater cognisance of goal-concordant care and for studies to provide an evidence basis for treatment breaks.

Identifiers

PMID41266597
PMCPMC12635393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.