Evidence map›Paper›PMID 41266564›Full record

ArticleNPJ Parkinson's disease2025

Added value of a wrist-worn device for assessing tremor in Parkinson's disease: reliability and validity of tremor evaluation at home.

D H Hepp, K Ocran, A Szanto, J J van Hilten, V Exadaktylos, R H A Weijer

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D H Hepp *Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
K Ocran *Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
A SzantoOccamzRazor, New York, NY, USA.
J J van HiltenDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
V ExadaktylosCentre for Human Drug Research, Leiden, The Netherlands.
R H A WeijerDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands. r.h.a.weijer@lumc.nl.

Funding

ZonMw,The Netherlands 460001001
6 · The paper itself

Abstract

Clinical assessment and self-report of tremor in Parkinson's disease (PD) have several limitations, including recall bias and lack of sensitivity. Wearable-based technology offers an opportunity to address these shortcomings. We investigated the test-retest reliability of wearable tremor assessment and compared the different approaches of assessing tremor. We analyzed data from 219 participants of the ProPark study. In 27% of people with PD, self-report and clinical observation disagreed about the presence of tremor. Wearable-based tremor assessment had excellent test-retest reliability after 3 days of data recording (ICC(2,3) lower bound of 95%CI > 0.90 for all tremor metrics). Wearable-derived tremor amplitude, duration, and volume were significantly associated with clinical assessment of tremor (all p < 0.001), and tremor volume was consistent with patient self-report of tremor presence when clinical observation failed to detect tremor (p = 0.040). In conclusion, wearable sensors can provide accurate and relevant information about the presence and severity of tremor in PD.

Identifiers

PMID41266564
PMCPMC12635349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.